4AGS

Leishmania TDR1 - a unique trimeric glutathione transferase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	THIOL-DEPENDENT REDUCTASE 1	polymer	471	53195.8	3	UniProt (A4I8P2) Pfam (PF13409) Pfam (PF16865)	LEISHMANIA INFANTUM
2	D, E, L, M, S... (A, B, C)	GLUTATHIONE	non-polymer		307.3	6	Chemie (GSH)
3	F, G, H, I, J... (A, B, C)	1,2-ETHANEDIOL	non-polymer		62.1	15	Chemie (EDO)
4	AA, Y, Z (C, A, B)	water	water		18.0	1165	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 450 (UniProt: A4I8P2)

PDB	External Database	Details
Mse -20	-	expression tag
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	159587.5
Non-Polymers*	Number of molecules	21
	Total formula weight	2775.0
All*	Total formula weight	162362.5

*Water molecules are not included.