4YDF
Crystal structure of compound 9 in complex with HTLV-1 Protease
Summary for 4YDF
Entry DOI | 10.2210/pdb4ydf/pdb |
Related | 3LIX 3WSJ |
Descriptor | HTLV-1 Protease, N-benzyl-N-[(3S,4S)-4-{benzyl[(4-nitrophenyl)sulfonyl]amino}pyrrolidin-3-yl]-3-nitrobenzenesulfonamide, SULFATE ION, ... (4 entities in total) |
Functional Keywords | htlv-1 protease, hydrolase |
Biological source | Human T-lymphotropic virus 1 |
Total number of polymer chains | 2 |
Total formula weight | 25880.93 |
Authors | Kuhnert, M.,Blum, A.,Steuber, H.,Diederich, W.E. (deposition date: 2015-02-22, release date: 2016-02-03, Last modification date: 2024-01-10) |
Primary citation | Kuhnert, M.,Blum, A.,Steuber, H.,Diederich, W.E. Privileged Structures Meet Human T-Cell Leukemia Virus-1 (HTLV-1): C2-Symmetric 3,4-Disubstituted Pyrrolidines as Nonpeptidic HTLV-1 Protease Inhibitors. J.Med.Chem., 58:4845-4850, 2015 Cited by PubMed: 26000468DOI: 10.1021/acs.jmedchem.5b00346 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.804 Å) |
Structure validation
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