4YPO

Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase in complex with Mg2+

Summary for 4YPO

Entry DOI	10.2210/pdb4ypo/pdb
Descriptor	Ketol-acid reductoisomerase, MAGNESIUM ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	ilvc, branch chain amino acids, knotted protein, rossmann fold, oxidoreductase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	2
Total formula weight	72677.91
Authors	Lv, Y.,Guddat, L.W. (deposition date: 2015-03-13, release date: 2016-02-17, Last modification date: 2024-02-28)
Primary citation	Lv, Y.,Kandale, A.,Wun, S.J.,McGeary, R.P.,Williams, S.J.,Kobe, B.,Sieber, V.,Schembri, M.A.,Schenk, G.,Guddat, L.W. Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase at 1.0 angstrom resolution - a potential target for anti-tuberculosis drug discovery. Febs J., 283:1184-1196, 2016 Cited by PubMed: 26876563 DOI: 10.1111/febs.13672 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.001 Å)

Structure validation