4YPO
Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase in complex with Mg2+
Summary for 4YPO
Entry DOI | 10.2210/pdb4ypo/pdb |
Descriptor | Ketol-acid reductoisomerase, MAGNESIUM ION, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | ilvc, branch chain amino acids, knotted protein, rossmann fold, oxidoreductase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 2 |
Total formula weight | 72677.91 |
Authors | Lv, Y.,Guddat, L.W. (deposition date: 2015-03-13, release date: 2016-02-17, Last modification date: 2024-02-28) |
Primary citation | Lv, Y.,Kandale, A.,Wun, S.J.,McGeary, R.P.,Williams, S.J.,Kobe, B.,Sieber, V.,Schembri, M.A.,Schenk, G.,Guddat, L.W. Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase at 1.0 angstrom resolution - a potential target for anti-tuberculosis drug discovery. Febs J., 283:1184-1196, 2016 Cited by PubMed: 26876563DOI: 10.1111/febs.13672 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.001 Å) |
Structure validation
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