6Z7T
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![BU of 6z7t by Molmil](/molmil-images/mine/6z7t) | Nucleotide-free Myosin-II motor domain | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Ewert, W, Preller, M. | 登録日 | 2020-06-01 | 公開日 | 2020-10-21 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Structural and Computational Insights into a Blebbistatin-Bound Myosin•ADP Complex with Characteristics of an ADP-Release Conformation along the Two-Step Myosin Power Stoke. Int J Mol Sci, 21, 2020
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6S0R
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![BU of 6s0r by Molmil](/molmil-images/mine/6s0r) | The crystal structure of kanamycin B dioxygenase (KanJ) from Streptomyces kanamyceticus complex with nickel, sulfate and chloride | 分子名称: | CHLORIDE ION, Kanamycin B dioxygenase, NICKEL (II) ION, ... | 著者 | Mrugala, B, Porebski, P.J, Niedzialkowska, E, Cymborowski, M.T, Minor, W, Borowski, T. | 登録日 | 2019-06-18 | 公開日 | 2020-07-08 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A study on the structure, mechanism, and biochemistry of kanamycin B dioxygenase (KanJ)-an enzyme with a broad range of substrates. Febs J., 288, 2021
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7BIM
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![BU of 7bim by Molmil](/molmil-images/mine/7bim) | A de novo designed nonameric coiled coil, CC-Type2-(GgLaId)4 | 分子名称: | GLYCEROL, ISOPROPYL ALCOHOL, Nonameric de novo coiled coil CC-Type2-(GgLaId)4 | 著者 | Shelley, K.L, Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. | 登録日 | 2021-01-12 | 公開日 | 2021-04-21 | 最終更新日 | 2021-11-17 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Coiled coils 9-to-5: rational de novo design of alpha-helical barrels with tunable oligomeric states. Chem Sci, 12, 2021
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1HBO
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![BU of 1hbo by Molmil](/molmil-images/mine/1hbo) | METHYL-COENZYME M REDUCTASE MCR-RED1-SILENT | 分子名称: | 1-THIOETHANESULFONIC ACID, CHLORIDE ION, Coenzyme B, ... | 著者 | Grabarse, W. | 登録日 | 2001-04-20 | 公開日 | 2001-08-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | On the Mechanism of Biological Methane Formation: Structural Evidence for Conformational Changes in Methyl-Coenzyme M Reductase Upon Substrate Binding J.Mol.Biol., 309, 2001
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7BZW
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![BU of 7bzw by Molmil](/molmil-images/mine/7bzw) | Structure of Hsp21 | 分子名称: | Heat shock protein 21, chloroplastic | 著者 | Lau, W.C.Y. | 登録日 | 2020-04-28 | 公開日 | 2021-04-28 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structural basis of substrate recognition and thermal protection by a small heat shock protein. Nat Commun, 12, 2021
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5I3L
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![BU of 5i3l by Molmil](/molmil-images/mine/5i3l) | DPF3b in complex with H3K14ac peptide | 分子名称: | 1,2-ETHANEDIOL, H3K14ac peptide, SODIUM ION, ... | 著者 | Tempel, W, Liu, Y, Walker, J.R, Zhao, A, Qin, S, Loppnau, P, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2016-02-10 | 公開日 | 2016-02-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of DPF3b in complex with an acetylated histone peptide. J.Struct.Biol., 195, 2016
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8OIO
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![BU of 8oio by Molmil](/molmil-images/mine/8oio) | Crystal structure of the kelch domain of human KLHL12 in complex with PLEKHA4 peptide | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Kelch-like protein 12, ... | 著者 | Dalietou, E.V, Chen, Z, Ramdass, A.E, Manning, C, Richardson, W, Aitmakhanova, K, Platt, M, Pike, A.C.W, Fedorov, O, Brennan, P, Bullock, A.N. | 登録日 | 2023-03-23 | 公開日 | 2024-04-03 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.954 Å) | 主引用文献 | Crystal structure of the kelch domain of human KLHL12 in complex with PLEKHA4 peptide To Be Published
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6R82
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![BU of 6r82 by Molmil](/molmil-images/mine/6r82) | |
7U8Y
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![BU of 7u8y by Molmil](/molmil-images/mine/7u8y) | TREX1 Structural Studies Capture Small Molecule Inhibition and Implicate Novel DNA Dynamics | 分子名称: | ALIZARIN RED, MANGANESE (II) ION, Three-prime repair exonuclease 1 | 著者 | Hemphill, W.O, Harvey, S.E, Simpson, S.R, Smalley, T.L, Salsbury, F.R, Perrino, F.W, Hollis, T. | 登録日 | 2022-03-09 | 公開日 | 2023-03-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | TREX1 Structural Studies Capture Small Molecule Inhibition and Implicate Novel DNA Dynamics to be published
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8AEW
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![BU of 8aew by Molmil](/molmil-images/mine/8aew) | |
7AR7
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![BU of 7ar7 by Molmil](/molmil-images/mine/7ar7) | Cryo-EM structure of Arabidopsis thaliana complex-I (open conformation) | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, ... | 著者 | Klusch, N, Kuelbrandt, W. | 登録日 | 2020-10-23 | 公開日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | 主引用文献 | A ferredoxin bridge connects the two arms of plant mitochondrial complex I. Plant Cell, 33, 2021
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6ZDV
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![BU of 6zdv by Molmil](/molmil-images/mine/6zdv) | Crystal structure of stabilized A2A adenosine receptor A2AR-StaR2-bRIL in complex with Chromone 5d | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a, ... | 著者 | Verdon, G, Jespers, W, Azuaje, J, Majellaro, M, Keranen, H, Garcia-mera, X, Congreve, M, Deflorian, F, de Graaf, C, Zhukov, A, Dore, A, Mason, J, Aqvist, J, Cooke, R, Sotelo, E, Gutierrez-de-Teran, H. | 登録日 | 2020-06-15 | 公開日 | 2020-09-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | X-Ray Crystallography and Free Energy Calculations Reveal the Binding Mechanism of A 2A Adenosine Receptor Antagonists. Angew.Chem.Int.Ed.Engl., 59, 2020
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6ZJ3
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![BU of 6zj3 by Molmil](/molmil-images/mine/6zj3) | Cryo-EM structure of the highly atypical cytoplasmic ribosome of Euglena gracilis | 分子名称: | 18S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Matzov, D, Halfon, H, Zimmerman, E, Rozenberg, H, Bashan, A, Gray, M.W, Yonath, A.E, Shalev-Benami, M. | 登録日 | 2020-06-27 | 公開日 | 2020-10-07 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Cryo-EM structure of the highly atypical cytoplasmic ribosome of Euglena gracilis. Nucleic Acids Res., 48, 2020
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6ZH8
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![BU of 6zh8 by Molmil](/molmil-images/mine/6zh8) | Cryo-EM structure of DNA-PKcs:DNA | 分子名称: | DNA (5'-D(P*AP*CP*TP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*AP*GP*TP*TP*TP*TP*TP*AP*GP*TP*T)-3'), DNA-dependent protein kinase catalytic subunit,DNA-PKcs | 著者 | Chaplin, A.K, Hardwick, S.W, Chirgadze, D.Y, Blundell, T.L. | 登録日 | 2020-06-21 | 公開日 | 2020-10-21 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.14 Å) | 主引用文献 | Dimers of DNA-PK create a stage for DNA double-strand break repair. Nat.Struct.Mol.Biol., 28, 2021
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1NSD
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![BU of 1nsd by Molmil](/molmil-images/mine/1nsd) | INFLUENZA B VIRUS NEURAMINIDASE CAN SYNTHESIZE ITS OWN INHIBITOR | 分子名称: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Burmeister, W.P, Ruigrok, R.W.H, Cusack, S. | 登録日 | 1993-05-24 | 公開日 | 1993-10-31 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Influenza B virus neuraminidase can synthesize its own inhibitor. Structure, 1, 1993
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1GP5
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![BU of 1gp5 by Molmil](/molmil-images/mine/1gp5) | Anthocyanidin synthase from Arabidopsis thaliana complexed with trans-dihydroquercetin | 分子名称: | (2R,3R)-2-(3,4-DIHYDROXYPHENYL)-3,5,7-TRIHYDROXY-2,3-DIHYDRO-4H-CHROMEN-4-ONE, (2S,3S)-2-(3,4-DIHYDROXYPHENYL)-3,5,7-TRIHYDROXY-2,3-DIHYDRO-4H-CHROMEN-4-ONE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | 著者 | Wilmouth, R.C, Turnbull, J.J, Welford, R.W.D, Clifton, I.J, Prescott, A.G, Schofield, C.J. | 登録日 | 2001-10-30 | 公開日 | 2002-02-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure and Mechanism of Anthocyanidin Synthase from Arabidopsis Thaliana. Structure, 10, 2002
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7SA3
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![BU of 7sa3 by Molmil](/molmil-images/mine/7sa3) | Structure of a monomeric photosystem II core complex from a cyanobacterium acclimated to far-red light | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 2,3-DIMETHYL-5-(3,7,11,15,19,23,27,31,35-NONAMETHYL-2,6,10,14,18,22,26,30,34-HEXATRIACONTANONAENYL-2,5-CYCLOHEXADIENE-1,4-DIONE-2,3-DIMETHYL-5-SOLANESYL-1,4-BENZOQUINONE, ... | 著者 | Gisriel, C.J, Bryant, D.A, Brudvig, G.W. | 登録日 | 2021-09-22 | 公開日 | 2021-12-01 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.25 Å) | 主引用文献 | Structure of a monomeric photosystem II core complex from a cyanobacterium acclimated to far-red light reveals the functions of chlorophylls d and f. J.Biol.Chem., 298, 2021
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1H8Z
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![BU of 1h8z by Molmil](/molmil-images/mine/1h8z) | Crystal structure of the class D beta-lactamase OXA-13 | 分子名称: | BETA-LACTAMASE, SULFATE ION | 著者 | Pernot, L, Frenois, F, Rybkine, T, L'Hermite, G, Petrella, S, Delettre, J, Jarlier, V, Collatz, E, Sougakoff, W. | 登録日 | 2001-02-17 | 公開日 | 2001-07-12 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structures of the Class D B-Lactamase Oxa-13 in the Native Form and in Complex with Meropenem J.Mol.Biol., 310, 2001
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6LRR
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![BU of 6lrr by Molmil](/molmil-images/mine/6lrr) | Cryo-EM structure of RuBisCO-Raf1 from Anabaena sp. PCC 7120 | 分子名称: | All5250 protein, Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small chain | 著者 | Xia, L.Y, Jiang, Y.L, Kong, W.W, Chen, Y, Zhou, C.Z. | 登録日 | 2020-01-16 | 公開日 | 2020-05-13 | 最終更新日 | 2020-07-01 | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | 主引用文献 | Molecular basis for the assembly of RuBisCO assisted by the chaperone Raf1. Nat.Plants, 6, 2020
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6LUM
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![BU of 6lum by Molmil](/molmil-images/mine/6lum) | Structure of Mycobacterium smegmatis succinate dehydrogenase 2 | 分子名称: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, ... | 著者 | Gao, Y, Gong, H, Zhou, X, Xiao, Y, Wang, W, Ji, W, Wang, Q, Rao, Z. | 登録日 | 2020-01-29 | 公開日 | 2020-05-27 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | Cryo-EM structure of trimeric Mycobacterium smegmatis succinate dehydrogenase with a membrane-anchor SdhF. Nat Commun, 11, 2020
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3D94
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![BU of 3d94 by Molmil](/molmil-images/mine/3d94) | Crystal structure of the insulin-like growth factor-1 receptor kinase in complex with PQIP | 分子名称: | 3-[cis-3-(4-methylpiperazin-1-yl)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine, CALCIUM ION, Insulin-like growth factor 1 receptor beta chain | 著者 | Wu, J, Li, W, Miller, W.T, Hubbard, S.R. | 登録日 | 2008-05-26 | 公開日 | 2008-07-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Small-molecule inhibition and activation-loop trans-phosphorylation of the IGF1 receptor Embo J., 27, 2008
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8X7A
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![BU of 8x7a by Molmil](/molmil-images/mine/8x7a) | Treprostinil bound Prostacyclin Receptor G protein complex | 分子名称: | 2-[[(1~{R},2~{R},3~{a}~{S},9~{a}~{S})-2-oxidanyl-1-[(3~{S})-3-oxidanyloctyl]-2,3,3~{a},4,9,9~{a}-hexahydro-1~{H}-cyclopenta[g]naphthalen-5-yl]oxy]ethanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Wang, J.J, Jin, S, Zhang, H, Xu, Y, Hu, W, Jiang, Y, Chen, C, Wang, D.W, Xu, H.E, Wu, C. | 登録日 | 2023-11-23 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | 主引用文献 | Molecular recognition and activation of the prostacyclin receptor by anti-pulmonary arterial hypertension drugs. Sci Adv, 10, 2024
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6TP9
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![BU of 6tp9 by Molmil](/molmil-images/mine/6tp9) | c-type cytochrome NirC | 分子名称: | Cytochrome c55X, HEME C | 著者 | Kluenemann, T, Henke, S, Blankenfeldt, W. | 登録日 | 2019-12-12 | 公開日 | 2020-04-22 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | The crystal structure of the heme d1biosynthesis-associated small c-type cytochrome NirC reveals mixed oligomeric states in crystallo. Acta Crystallogr D Struct Biol, 76, 2020
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6T9N
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![BU of 6t9n by Molmil](/molmil-images/mine/6t9n) | CryoEM structure of human polycystin-2/PKD2 in UDM supplemented with PI(4,5)P2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Wang, Q, Pike, A.C.W, Grieben, M, Baronina, A, Nasrallah, C, Shintre, C, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2019-10-28 | 公開日 | 2019-11-20 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | 主引用文献 | Lipid Interactions of a Ciliary Membrane TRP Channel: Simulation and Structural Studies of Polycystin-2. Structure, 28, 2020
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8X79
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![BU of 8x79 by Molmil](/molmil-images/mine/8x79) | MRE-269 bound Prostacyclin Receptor G protein complex | 分子名称: | 2-[4-[(5,6-diphenylpyrazin-2-yl)-propan-2-yl-amino]butoxy]ethanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Wang, J.J, Jin, S, Zhang, H, Xu, Y, Hu, W, Jiang, Y, Chen, C, Wang, D.W, Xu, H.E, Wu, C. | 登録日 | 2023-11-23 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.41 Å) | 主引用文献 | Molecular recognition and activation of the prostacyclin receptor by anti-pulmonary arterial hypertension drugs. Sci Adv, 10, 2024
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