8X7A
Treprostinil bound Prostacyclin Receptor G protein complex
Summary for 8X7A
Entry DOI | 10.2210/pdb8x7a/pdb |
EMDB information | 38096 |
Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,GNAS complex locus, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | agonist, complex, lipid receptor, signaling protein |
Biological source | Homo sapiens More |
Total number of polymer chains | 5 |
Total formula weight | 131637.97 |
Authors | Wang, J.J.,Jin, S.,Zhang, H.,Xu, Y.,Hu, W.,Jiang, Y.,Chen, C.,Wang, D.W.,Xu, H.E.,Wu, C. (deposition date: 2023-11-23, release date: 2024-03-06) |
Primary citation | Wang, J.J.,Jin, S.,Zhang, H.,Xu, Y.,Hu, W.,Jiang, Y.,Chen, C.,Wang, D.W.,Xu, H.E.,Wu, C. Molecular recognition and activation of the prostacyclin receptor by anti-pulmonary arterial hypertension drugs. Sci Adv, 10:eadk5184-eadk5184, 2024 Cited by PubMed: 38335293DOI: 10.1126/sciadv.adk5184 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.56 Å) |
Structure validation
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