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7U8Y

TREX1 Structural Studies Capture Small Molecule Inhibition and Implicate Novel DNA Dynamics

Summary for 7U8Y
Entry DOI10.2210/pdb7u8y/pdb
DescriptorThree-prime repair exonuclease 1, ALIZARIN RED, MANGANESE (II) ION, ... (4 entities in total)
Functional Keywordsinhibitor, exonuclease, immunotherapy, complex, dna binding protein, hydrolase-inhibitor complex, hydrolase/inhibitor
Biological sourceMus musculus (house mouse)
Total number of polymer chains2
Total formula weight51678.12
Authors
Hemphill, W.O.,Harvey, S.E.,Simpson, S.R.,Smalley, T.L.,Salsbury, F.R.,Perrino, F.W.,Hollis, T. (deposition date: 2022-03-09, release date: 2023-03-15, Last modification date: 2023-10-25)
Primary citationHemphill, W.O.,Harvey, S.E.,Simpson, S.R.,Smalley, T.L.,Salsbury, F.R.,Perrino, F.W.,Hollis, T.
TREX1 Structural Studies Capture Small Molecule Inhibition and Implicate Novel DNA Dynamics
to be published,
Experimental method
Structure validation

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