7U8Y

TREX1 Structural Studies Capture Small Molecule Inhibition and Implicate Novel DNA Dynamics

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Three-prime repair exonuclease 1	polymer	229	25088.6	2	UniProt (Q91XB0)	Mus musculus (house mouse)	3'-5' exonuclease TREX1
2	C, D, G, H (A, B)	ALIZARIN RED	non-polymer		320.3	4	Chemie (AZN)
3	E, F, I, J (A, B)	MANGANESE (II) ION	non-polymer		54.9	4	Chemie (MN)
4	K, L (A, B)	water	water		18.0	124	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	50177.3
Non-Polymers*	Number of molecules	8
	Total formula weight	1500.8
All*	Total formula weight	51678.1

*Water molecules are not included.