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7U8Y

TREX1 Structural Studies Capture Small Molecule Inhibition and Implicate Novel DNA Dynamics

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BThree-prime repair exonuclease 1polymer22925088.62UniProt (Q91XB0)
In PDB
Mus musculus (house mouse)3'-5' exonuclease TREX1
2A, BALIZARIN REDnon-polymer320.34Chemie (AZN)
3A, BMANGANESE (II) IONnon-polymer54.94Chemie (MN)
4waterwater18.0124Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight50177.3
Non-Polymers*Number of molecules8
Total formula weight1500.8
All*Total formula weight51678.1
*Water molecules are not included.

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PDB entries from 2024-10-16

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