8X79

MRE-269 bound Prostacyclin Receptor G protein complex

Summary for 8X79

• Entry DOI: 10.2210/pdb8x79/pdb
• EMDB information: 38095
• Descriptor: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,GNAS complex locus,GNAS complex locus, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: agonist, complex, lipid receptor, signaling protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 5
• Total formula weight: 131666.97

Authors

Wang, J.J.,Jin, S.,Zhang, H.,Xu, Y.,Hu, W.,Jiang, Y.,Chen, C.,Wang, D.W.,Xu, H.E.,Wu, C. (deposition date: 2023-11-23, release date: 2024-03-06)

• Primary citation: Wang, J.J.,Jin, S.,Zhang, H.,Xu, Y.,Hu, W.,Jiang, Y.,Chen, C.,Wang, D.W.,Xu, H.E.,Wu, C.; Molecular recognition and activation of the prostacyclin receptor by anti-pulmonary arterial hypertension drugs.; Sci Adv, 10:eadk5184-eadk5184, 2024; PubMed: 38335293; DOI: 10.1126/sciadv.adk5184

Experimental method

ELECTRON MICROSCOPY (2.41 Å)