213L
| PROTEIN STRUCTURE PLASTICITY EXEMPLIFIED BY INSERTION AND DELETION MUTANTS IN T4 LYSOZYME | 分子名称: | T4 LYSOZYME | 著者 | Vetter, I.R, Baase, W.A, Heinz, D.W, Xiong, J.-P, Snow, S, Matthews, B.W. | 登録日 | 1996-09-23 | 公開日 | 1996-12-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Protein structural plasticity exemplified by insertion and deletion mutants in T4 lysozyme. Protein Sci., 5, 1996
|
|
212L
| PROTEIN STRUCTURE PLASTICITY EXEMPLIFIED BY INSERTION AND DELETION MUTANTS IN T4 LYSOZYME | 分子名称: | 2-HYDROXYETHYL DISULFIDE, T4 LYSOZYME | 著者 | Vetter, I.R, Baase, W.A, Heinz, D.W, Xiong, J.-P, Snow, S, Matthews, B.W. | 登録日 | 1996-09-23 | 公開日 | 1996-12-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Protein structural plasticity exemplified by insertion and deletion mutants in T4 lysozyme. Protein Sci., 5, 1996
|
|
214L
| PROTEIN STRUCTURE PLASTICITY EXEMPLIFIED BY INSERTION AND DELETION MUTANTS IN T4 LYSOZYME | 分子名称: | T4 LYSOZYME | 著者 | Vetter, I.R, Baase, W.A, Heinz, D.W, Xiong, J.-P, Snow, S, Matthews, B.W. | 登録日 | 1996-09-23 | 公開日 | 1996-12-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Protein structural plasticity exemplified by insertion and deletion mutants in T4 lysozyme. Protein Sci., 5, 1996
|
|
209L
| PROTEIN STRUCTURE PLASTICITY EXEMPLIFIED BY INSERTION AND DELETION MUTANTS IN T4 LYSOZYME | 分子名称: | T4 LYSOZYME | 著者 | Vetter, I.R, Baase, W.A, Heinz, D.W, Xiong, J.-P, Snow, S, Matthews, B.W. | 登録日 | 1996-09-23 | 公開日 | 1996-12-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Protein structural plasticity exemplified by insertion and deletion mutants in T4 lysozyme. Protein Sci., 5, 1996
|
|
215L
| PROTEIN STRUCTURE PLASTICITY EXEMPLIFIED BY INSERTION AND DELETION MUTANTS IN T4 LYSOZYME | 分子名称: | 2-HYDROXYETHYL DISULFIDE, T4 LYSOZYME | 著者 | Vetter, I.R, Baase, W.A, Heinz, D.W, Xiong, J.-P, Snow, S, Matthews, B.W. | 登録日 | 1996-09-23 | 公開日 | 1996-12-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Protein structural plasticity exemplified by insertion and deletion mutants in T4 lysozyme. Protein Sci., 5, 1996
|
|
8RKQ
| Structure of human DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE (ALDH4A1) complexed with the molecular tweezer CLR01 | 分子名称: | (1R,5S,9S,16R,20R,24S,28S,35R)-3,22-Bis(dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaene, Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 著者 | Porfetye, A.T, Vetter, I.R. | 登録日 | 2023-12-28 | 公開日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | How Do Molecular Tweezers Bind to Proteins? Lessons from X-ray Crystallography. Molecules, 29, 2024
|
|
8RKR
| Structure of human DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE (ALDH4A1) complexed with a monophosphate-tweezer | 分子名称: | (1R,5S,9S,16R,20R,24S,28S,35R)-22-(Dihydroxyphosphoryloxy)tridecacyclo[22.14.1.15,20.19,16.128,35.02,23.04,21.06,19.08,17.010,15.025,38.027,36.029,34]dotetraconta-2(23),3,6,8(17),10,12,14,18,21,25,27(36),29,31,33,37-pentadecaen-3-ol, BENZOIC ACID, Delta-1-pyrroline-5-carboxylate dehydrogenase, ... | 著者 | Porfetye, A.T, Vetter, I.R. | 登録日 | 2023-12-28 | 公開日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | How Do Molecular Tweezers Bind to Proteins? Lessons from X-ray Crystallography. Molecules, 29, 2024
|
|
1K5G
| Crystal structure of Ran-GDP-AlFx-RanBP1-RanGAP complex | 分子名称: | ALUMINUM FLUORIDE, GTP-binding nuclear protein RAN, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Seewald, M.J, Koerner, C, Wittinghofer, A, Vetter, I.R. | 登録日 | 2001-10-10 | 公開日 | 2002-02-13 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | RanGAP mediates GTP hydrolysis without an arginine finger. Nature, 415, 2002
|
|
1K5D
| Crystal structure of Ran-GPPNHP-RanBP1-RanGAP complex | 分子名称: | GTP-binding nuclear protein RAN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Seewald, M.J, Koerner, C, Wittinghofer, A, Vetter, I.R. | 登録日 | 2001-10-10 | 公開日 | 2002-02-13 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | RanGAP mediates GTP hydrolysis without an arginine finger. Nature, 415, 2002
|
|
6C0W
| Cryo-EM structure of human kinetochore protein CENP-N with the centromeric nucleosome containing CENP-A | 分子名称: | 147 mer DNA, Centromere protein N, Histone H2A, ... | 著者 | Zhou, K, Pentakota, S, Vetter, I.R, Morgan, G.P, Petrovic, A, Musacchio, A, Luger, K. | 登録日 | 2018-01-02 | 公開日 | 2018-01-17 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Decoding the centromeric nucleosome through CENP-N. Elife, 6, 2017
|
|
3T1Q
| MglA bound to GppNHp in complex with MglB | 分子名称: | Gliding protein MglB, Gliding protein mglA, MAGNESIUM ION, ... | 著者 | Miertzschke, M, Vetter, I.R, Koerner, C, Wittinghofer, A. | 登録日 | 2011-07-22 | 公開日 | 2011-08-31 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity. Embo J., 30, 2011
|
|
1IAQ
| C-H-RAS P21 PROTEIN MUTANT WITH THR 35 REPLACED BY SER (T35S) COMPLEXED WITH GUANOSINE-5'-[B,G-IMIDO] TRIPHOSPHATE | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, TRANSFORMING PROTEIN P21/H-RAS-1 | 著者 | Spoerner, M, Herrmann, C, Vetter, I.R, Kalbitzer, H.R, Wittinghofer, A. | 登録日 | 2001-03-23 | 公開日 | 2001-06-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Dynamic properties of the Ras switch I region and its importance for binding to effectors. Proc.Natl.Acad.Sci.USA, 98, 2001
|
|
8P0S
| Crystal structure HR1 domain of Rho-associated coiled-coil protein kinases (ROCK-HR1) | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Rho-associated protein kinase 1 | 著者 | Dubey, B.N, Dvorsky, R, Gremer, L, Vetter, I.R, Schmitt, L, Groth, G, Ahmadian, M.R. | 登録日 | 2023-05-10 | 公開日 | 2023-06-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and functional insights into the p160 Rho-associated coiled-coil-containing protein kinase To Be Published
|
|
5T4R
| |
8A4B
| Structure of human Rep15:Rab3B_Q81L complex. | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rab15 effector protein, ... | 著者 | Rai, A, Vetter, I.R, Goody, R.S. | 登録日 | 2022-06-10 | 公開日 | 2022-08-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector. Nat Commun, 13, 2022
|
|
8A4C
| Structure of human Rep15:Rab3B complex. | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Rab15 effector protein, ... | 著者 | Rai, A, Vetter, I.R, Goody, R.S. | 登録日 | 2022-06-10 | 公開日 | 2022-08-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector. Nat Commun, 13, 2022
|
|
8Q5H
| Human KMN network (outer kinetochore) | 分子名称: | Kinetochore protein Spc24, Kinetochore protein Spc25, Kinetochore scaffold 1, ... | 著者 | Raisch, T, Polley, S, Vetter, I, Musacchio, A, Raunser, S. | 登録日 | 2023-08-09 | 公開日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Insights into human outer kinetochore assembly and force transmission from a structure-function analysis of the KMN network To Be Published
|
|
8A4A
| Structure of human Rep15 in complex with bovine Rab3C. | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Rab15 effector protein, ... | 著者 | Rai, A, Vetter, I.R, Goody, R.S. | 登録日 | 2022-06-10 | 公開日 | 2022-08-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector. Nat Commun, 13, 2022
|
|
4O9Y
| Crystal Structure of TcdA1 | 分子名称: | TcdA1 | 著者 | Meusch, D, Gatsogiannis, C, Efremov, R.G, Lang, A.E, Hofnagel, O, Vetter, I.R, Aktories, K, Raunser, S. | 登録日 | 2014-01-03 | 公開日 | 2014-02-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.502 Å) | 主引用文献 | Mechanism of Tc toxin action revealed in molecular detail. Nature, 508, 2014
|
|
1M7B
| Crystal structure of Rnd3/RhoE: functional implications | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rnd3/RhoE small GTP-binding protein | 著者 | Fiegen, D, Blumenstein, L, Stege, P, Vetter, I.R, Ahmadian, M.R. | 登録日 | 2002-07-19 | 公開日 | 2002-08-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of Rnd3/RhoE: functional implications FEBS LETT., 525, 2002
|
|
7QPG
| Human RZZ kinetochore corona complex. | 分子名称: | Centromere/kinetochore protein zw10 homolog, Kinetochore-associated protein 1, Protein zwilch homolog | 著者 | Raisch, T, Ciossani, G, d'Amico, E, Cmetowski, V, Carmignani, S, Maffini, S, Merino, F, Wohlgemuth, S, Vetter, I.R, Raunser, S, Musacchio, A. | 登録日 | 2022-01-04 | 公開日 | 2022-03-16 | 最終更新日 | 2022-05-11 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structure of the RZZ complex and molecular basis of Spindly-driven corona assembly at human kinetochores. Embo J., 41, 2022
|
|
6SZQ
| Crystal structure of human DDAH-1 | 分子名称: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | 著者 | Hennig, S, Vetter, I.R, Schade, D. | 登録日 | 2019-10-02 | 公開日 | 2019-12-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.412 Å) | 主引用文献 | Discovery ofN-(4-Aminobutyl)-N'-(2-methoxyethyl)guanidine as the First Selective, Nonamino Acid, Catalytic Site Inhibitor of Human Dimethylarginine Dimethylaminohydrolase-1 (hDDAH-1). J.Med.Chem., 63, 2020
|
|
1A4R
| G12V MUTANT OF HUMAN PLACENTAL CDC42 GTPASE IN THE GDP FORM | 分子名称: | AMINOPHOSPHONIC ACID-GUANYLATE ESTER, G25K GTP-BINDING PROTEIN, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Rudolph, M.G, Vetter, I.R, Wittinghofer, A. | 登録日 | 1998-02-02 | 公開日 | 1999-03-02 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Nucleotide binding to the G12V-mutant of Cdc42 investigated by X-ray diffraction and fluorescence spectroscopy: two different nucleotide states in one crystal. Protein Sci., 8, 1999
|
|
3L8Y
| Complex of Ras with cyclen | 分子名称: | 1,4,7,10-tetraazacyclododecane, CALCIUM ION, GTPase HRas, ... | 著者 | Rosnizeck, I.C, Graf, T, Spoerner, M, Traenkle, J, Filchtinski, D, Herrmann, C, Gremer, L, Vetter, I.R, Wittinghofer, A, Koenig, B, Kalbitzer, H.R. | 登録日 | 2010-01-04 | 公開日 | 2011-01-05 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Stabilizing a weak binding state for effectors in the human ras protein by cyclen complexes Angew.Chem.Int.Ed.Engl., 49, 2010
|
|
4GOJ
| The Crystal Structure of full length Arl3GppNHp in complex with UNC119a | 分子名称: | ADP-ribosylation factor-like protein 3, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Ismail, S, Xiang-Chen, Y, Miertzschke, M, Vetter, I, Koerner, C, Wittinghofer, A. | 登録日 | 2012-08-20 | 公開日 | 2012-09-19 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for Arl3-specific release of myristoylated ciliary cargo from UNC119. Embo J., 31, 2012
|
|