1A4R

G12V MUTANT OF HUMAN PLACENTAL CDC42 GTPASE IN THE GDP FORM

Summary for 1A4R

• Entry DOI: 10.2210/pdb1a4r/pdb
• Descriptor: G25K GTP-BINDING PROTEIN, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: hydrolase, gtpase, signal transduction
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane ; Lipid-anchor ; Cytoplasmic side : P60953
• Total number of polymer chains: 2
• Total formula weight: 43561.04

Authors

Rudolph, M.G.,Vetter, I.R.,Wittinghofer, A. (deposition date: 1998-02-02, release date: 1999-03-02, Last modification date: 2023-08-02)

• Primary citation: Rudolph, M.G.,Wittinghofer, A.,Vetter, I.R.; Nucleotide binding to the G12V-mutant of Cdc42 investigated by X-ray diffraction and fluorescence spectroscopy: two different nucleotide states in one crystal.; Protein Sci., 8:778-787, 1999; PubMed: 10211824

Experimental method

X-RAY DIFFRACTION (2.5 Å)