1A4R
G12V MUTANT OF HUMAN PLACENTAL CDC42 GTPASE IN THE GDP FORM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | G25K GTP-BINDING PROTEIN | polymer | 191 | 21325.7 | 2 | UniProt (P60953) Pfam (PF00071) | Homo sapiens (human) | G25K, CDC42 HOMOLOG |
| 2 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 3 | D (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 4 | E (B) | AMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 442.2 | 1 | Chemie (GNH) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 54 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 191 (UniProt: P60953)
| PDB | External Database | Details |
|---|---|---|
| Val 12 | Gly 12 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42651.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 909.7 | |
| All* | Total formula weight | 43561.0 |
