5T4R

NMR solution structure of the Nav1.7 selective spider venom-derived peptide Pn3a

Summary for 5T4R

Entry DOI	10.2210/pdb5t4r/pdb
NMR Information	BMRB: 30164
Descriptor	Mu-theraphotoxin-Pn3a (1 entity in total)
Functional Keywords	tarantula peptide toxin, inhibitor cystine knot, voltage-gated sodium channel modifier, voltage sensor modifier, toxin
Biological source	Theraphosidae (tarantulas)
Total number of polymer chains	1
Total formula weight	4285.99
Authors	Rosengren, K.J.,Armstrong, D.A.,Vetter, I. (deposition date: 2016-08-30, release date: 2017-09-06, Last modification date: 2023-06-14)
Primary citation	Deuis, J.R.,Dekan, Z.,Wingerd, J.S.,Smith, J.J.,Munasinghe, N.R.,Bhola, R.F.,Imlach, W.L.,Herzig, V.,Armstrong, D.A.,Rosengren, K.J.,Bosmans, F.,Waxman, S.G.,Dib-Hajj, S.D.,Escoubas, P.,Minett, M.S.,Christie, M.J.,King, G.F.,Alewood, P.F.,Lewis, R.J.,Wood, J.N.,Vetter, I. Pharmacological characterisation of the highly Na V 1.7 selective spider venom peptide Pn3a. Sci Rep, 7:40883-40883, 2017 Cited by PubMed: 28106092 DOI: 10.1038/srep40883 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation