8P0S
Crystal structure HR1 domain of Rho-associated coiled-coil protein kinases (ROCK-HR1)
Summary for 8P0S
Entry DOI | 10.2210/pdb8p0s/pdb |
Descriptor | Rho-associated protein kinase 1, 2,3-DIHYDROXY-1,4-DITHIOBUTANE (3 entities in total) |
Functional Keywords | coiled coil, hr1, rho kinase, rock, prk, pkn, rhotekin, signaling protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 32182.85 |
Authors | Dubey, B.N.,Dvorsky, R.,Gremer, L.,Vetter, I.R.,Schmitt, L.,Groth, G.,Ahmadian, M.R. (deposition date: 2023-05-10, release date: 2023-06-21) |
Primary citation | Dubey, B.N.,Amin, E.,Dvorsky, R.,Gremer, L.,Moll, J.M.,Wolff, M.,Graewert, M.,Tschapek, B.,Vetter, I.R.,Schmitt, L.,Svergun, D.,Raunser, R.,Groth, G.,Nagel-Steger, L.,Ahmadian, M.R. Structural and functional insights into the p160 Rho-associated coiled-coil-containing protein kinase To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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