3L8Y
Complex of Ras with cyclen
Summary for 3L8Y
Entry DOI | 10.2210/pdb3l8y/pdb |
Descriptor | GTPase HRas, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ... (7 entities in total) |
Functional Keywords | ras-ligand complex, cell membrane, disease mutation, golgi apparatus, gtp-binding, lipoprotein, methylation, nucleotide-binding, palmitate, prenylation, proto-oncogene, s-nitrosylation, oncoprotein |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane. Isoform 2: Nucleus: P01112 |
Total number of polymer chains | 1 |
Total formula weight | 19819.68 |
Authors | Rosnizeck, I.C.,Graf, T.,Spoerner, M.,Traenkle, J.,Filchtinski, D.,Herrmann, C.,Gremer, L.,Vetter, I.R.,Wittinghofer, A.,Koenig, B.,Kalbitzer, H.R. (deposition date: 2010-01-04, release date: 2011-01-05, Last modification date: 2023-11-01) |
Primary citation | Rosnizeck, I.C.,Graf, T.,Spoerner, M.,Trankle, J.,Filchtinski, D.,Herrmann, C.,Gremer, L.,Vetter, I.R.,Wittinghofer, A.,Konig, B.,Kalbitzer, H.R. Stabilizing a weak binding state for effectors in the human ras protein by cyclen complexes Angew.Chem.Int.Ed.Engl., 49:3830-3833, 2010 Cited by PubMed: 20401883DOI: 10.1002/anie.200907002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
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