Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 35 件
1Q57
DownloadVisualize
BU of 1q57 by Molmil
The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7
分子名称: DNA primase/helicase
著者Toth, E.A, Li, Y, Sawaya, M.R, Cheng, Y, Ellenberger, T.
登録日2003-08-06
公開日2003-11-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7
Mol.Cell, 12, 2003
6UAI
DownloadVisualize
BU of 6uai by Molmil
Imidazole-triggered RAS-specific subtilisin SUBT_BACAM complexed with YSAM peptide
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Toth, E.A, Bryan, P.N, Orban, J.
登録日2019-09-10
公開日2020-09-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Engineering subtilisin proteases that specifically degrade active RAS.
Commun Biol, 4, 2021
6UAO
DownloadVisualize
BU of 6uao by Molmil
Imidazole-triggered RAS-specific subtilisin SUBT_BACAM complexed with the peptide EEYSAM
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Peptide EEYSAM, ...
著者Toth, E.A, Bryan, P.N, Orban, J.
登録日2019-09-11
公開日2020-09-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Engineering subtilisin proteases that specifically degrade active RAS.
Commun Biol, 4, 2021
6UBE
DownloadVisualize
BU of 6ube by Molmil
Azide-triggered subtilisin SUBT_BACAM complexed with the peptide LFRAL
分子名称: AZIDE ION, GLYCEROL, Peptide LFRAL, ...
著者Toth, E.A, Bryan, P.N, Orban, J, Gallagher, D.T, Custer, G.
登録日2019-09-11
公開日2020-09-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Engineering subtilisin proteases that specifically degrade active RAS.
Commun Biol, 4, 2021
6U9L
DownloadVisualize
BU of 6u9l by Molmil
Imidazole-triggered RAS-specific subtilisin SUBT_BACAM
分子名称: GLYCEROL, POTASSIUM ION, SUBTILISIN BPN', ...
著者Toth, E.A, Bryan, P.N, Orban, J.
登録日2019-09-09
公開日2020-09-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Engineering subtilisin proteases that specifically degrade active RAS.
Commun Biol, 4, 2021
1C3C
DownloadVisualize
BU of 1c3c by Molmil
T. MARITIMA ADENYLOSUCCINATE LYASE
分子名称: PROTEIN (ADENYLOSUCCINATE LYASE)
著者Toth, E.A, Yeates, T.O.
登録日1999-07-27
公開日2000-02-09
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structure of adenylosuccinate lyase, an enzyme with dual activity in the de novo purine biosynthetic pathway.
Structure Fold.Des., 8, 2000
1C3U
DownloadVisualize
BU of 1c3u by Molmil
T. MARITIMA ADENYLOSUCCINATE LYASE
分子名称: ADENYLOSUCCINATE LYASE, SULFATE ION
著者Toth, E.A, Yeates, T.O.
登録日1999-07-28
公開日2000-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of adenylosuccinate lyase, an enzyme with dual activity in the de novo purine biosynthetic pathway.
Structure Fold.Des., 8, 2000
1DOF
DownloadVisualize
BU of 1dof by Molmil
THE CRYSTAL STRUCTURE OF ADENYLOSUCCINATE LYASE FROM PYROBACULUM AEROPHILUM: INSIGHTS INTO THERMAL STABILITY AND HUMAN PATHOLOGY
分子名称: ADENYLOSUCCINATE LYASE
著者Toth, E.A, Yeates, T.O, Goedken, E, Dixon, J.E, Marqusee, S.
登録日1999-12-20
公開日2001-01-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The crystal structure of adenylosuccinate lyase from Pyrobaculum aerophilum reveals an intracellular protein with three disulfide bonds.
J.Mol.Biol., 301, 2000
1F1O
DownloadVisualize
BU of 1f1o by Molmil
STRUCTURAL STUDIES OF ADENYLOSUCCINATE LYASES
分子名称: ADENYLOSUCCINATE LYASE
著者Toth, E.A, Yeates, T.
登録日2000-05-19
公開日2001-01-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献The crystal structure of adenylosuccinate lyase from Pyrobaculum aerophilum reveals an intracellular protein with three disulfide bonds.
J.Mol.Biol., 301, 2000
3N5N
DownloadVisualize
BU of 3n5n by Molmil
Crystal structure analysis of the catalytic domain and interdomain connector of human MutY homologue
分子名称: A/G-specific adenine DNA glycosylase, ACETATE ION, IRON/SULFUR CLUSTER
著者Toth, E.A, Luncsford, P.J.
登録日2010-05-25
公開日2010-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A structural hinge in eukaryotic MutY homologues mediates catalytic activity and Rad9-Rad1-Hus1 checkpoint complex interactions.
J.Mol.Biol., 403, 2010
5EA2
DownloadVisualize
BU of 5ea2 by Molmil
Crystal Structure of Holo NAD(P)H dehydrogenase, quinone 1
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H dehydrogenase [quinone] 1
著者Pidugu, L.S, Mbimba, J.E, Ahmad, M, Pozharski, E, Sausville, E.A, Emadi, A, Toth, E.A.
登録日2015-10-15
公開日2016-02-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献A direct interaction between NQO1 and a chemotherapeutic dimeric naphthoquinone.
Bmc Struct.Biol., 16, 2016
5EAI
DownloadVisualize
BU of 5eai by Molmil
Crystal Structure of NAD(P)H dehydrogenase, quinone 1 complexed with a chemotherapeutic naphthoquinone E6a
分子名称: (2~{R},3~{R})-2-[(2~{S},3~{S})-3-bromanyl-1,4-bis(oxidanylidene)-2,3-dihydronaphthalen-2-yl]-3-oxidanyl-2,3-dihydronaphthalene-1,4-dione, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H dehydrogenase [quinone] 1
著者Pidugu, L.S, Mbimba, J.E, Ahmad, M, Pozharski, E, Sausville, E.A, Emadi, A, Toth, E.A.
登録日2015-10-16
公開日2016-02-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A direct interaction between NQO1 and a chemotherapeutic dimeric naphthoquinone.
Bmc Struct.Biol., 16, 2016
4KWV
DownloadVisualize
BU of 4kwv by Molmil
Crystal Structure of human apo-QPRT
分子名称: Nicotinate-nucleotide pyrophosphorylase [carboxylating]
著者Malik, S.S, Patterson, D.N, Ncube, Z, Toth, E.A.
登録日2013-05-24
公開日2013-10-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.797 Å)
主引用文献The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid.
Proteins, 82, 2014
4KWW
DownloadVisualize
BU of 4kww by Molmil
The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid
分子名称: Nicotinate-nucleotide pyrophosphorylase [carboxylating], PHTHALIC ACID
著者Malik, S.S, Dimeka, P.N, Ncube, Z, Toth, E.A.
登録日2013-05-24
公開日2013-10-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid.
Proteins, 82, 2014
4LND
DownloadVisualize
BU of 4lnd by Molmil
Crystal structure of human apurinic/apyrimidinic endonuclease 1 with essential Mg2+ cofactor
分子名称: DNA-(apurinic or apyrimidinic site) lyase, MAGNESIUM ION
著者Manvilla, B.A, Pozharski, E, Toth, E.A, Drohat, A.C.
登録日2013-07-11
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structure of human apurinic/apyrimidinic endonuclease 1 with the essential Mg(2+) cofactor.
Acta Crystallogr.,Sect.D, 69, 2013
5DKR
DownloadVisualize
BU of 5dkr by Molmil
Crystal Structure of Calcium-loaded S100B bound to SBi29
分子名称: 2-[4-(4-carbamimidoylphenoxy)phenyl]-1H-indole-6-carboximidamide, CALCIUM ION, Protein S100-B
著者Cavalier, M.C, Ansari, M.I, Pierce, A.D, Wilder, P.T, McKnight, L.E, Raman, E.P, Neau, D.B, Bezawada, P, Alasady, M.J, Varney, K.M, Toth, E.A, MacKerell Jr, A.D, Coop, A, Weber, D.J.
登録日2015-09-03
公開日2016-01-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.742 Å)
主引用文献Small Molecule Inhibitors of Ca(2+)-S100B Reveal Two Protein Conformations.
J.Med.Chem., 59, 2016
5DKQ
DownloadVisualize
BU of 5dkq by Molmil
Crystal Structure of Calcium-loaded S100B bound to SBi4214
分子名称: 2,2'-[pentane-1,5-diylbis(oxybenzene-4,1-diyl)]di-1,4,5,6-tetrahydropyrimidine, CALCIUM ION, Protein S100-B
著者Cavalier, M.C, Ansari, M.I, Pierce, A.D, Wilder, P.T, McKnight, L.E, Raman, E.P, Neau, D.B, Bezawada, P, Alasady, M.J, Varney, K.M, Toth, E.A, MacKerell Jr, A.D, Coop, A, Weber, D.J.
登録日2015-09-03
公開日2016-01-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.591 Å)
主引用文献Small Molecule Inhibitors of Ca(2+)-S100B Reveal Two Protein Conformations.
J.Med.Chem., 59, 2016
5DKN
DownloadVisualize
BU of 5dkn by Molmil
Crystal Structure of Calcium-loaded S100B bound to SBi4225
分子名称: 2,2'-[heptane-1,7-diylbis(oxybenzene-4,1-diyl)]bis(1H-imidazole), CALCIUM ION, Protein S100-B
著者Cavalier, M.C, Ansari, M.I, Pierce, A.D, Wilder, P.T, McKnight, L.E, Raman, E.P, Neau, D.B, Bezawada, P, Alasady, M.J, Varney, K.M, Toth, E.A, MacKerell Jr, A.D, Coop, A, Weber, D.J.
登録日2015-09-03
公開日2016-01-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.528 Å)
主引用文献Small Molecule Inhibitors of Ca(2+)-S100B Reveal Two Protein Conformations.
J.Med.Chem., 59, 2016
5TKQ
DownloadVisualize
BU of 5tkq by Molmil
Crystal structure of human 3HAO with zinc bound in the active site
分子名称: 3-hydroxyanthranilate 3,4-dioxygenase, SULFATE ION, ZINC ION
著者Pidugu, L.S, Toth, E.A.
登録日2016-10-07
公開日2017-04-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structures of human 3-hydroxyanthranilate 3,4-dioxygenase with native and non-native metals bound in the active site.
Acta Crystallogr D Struct Biol, 73, 2017
5TK5
DownloadVisualize
BU of 5tk5 by Molmil
Crystal structure of human 3HAO with iron bound in the active site
分子名称: 3-hydroxyanthranilate 3,4-dioxygenase, FE (III) ION, SULFATE ION
著者Pidugu, L.S, Toth, E.A.
登録日2016-10-06
公開日2017-04-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Crystal structures of human 3-hydroxyanthranilate 3,4-dioxygenase with native and non-native metals bound in the active site.
Acta Crystallogr D Struct Biol, 73, 2017
3GK2
DownloadVisualize
BU of 3gk2 by Molmil
X-ray structure of bovine SBi279,Ca(2+)-S100B
分子名称: (Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide, CACODYLATE ION, CALCIUM ION, ...
著者Charpentier, T.H, Weber, D.J, Toth, E.A.
登録日2009-03-09
公開日2009-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.984 Å)
主引用文献Small molecules bound to unique sites in the target protein binding cleft of calcium-bound S100B as characterized by nuclear magnetic resonance and X-ray crystallography.
Biochemistry, 48, 2009
3GK4
DownloadVisualize
BU of 3gk4 by Molmil
X-ray structure of bovine SBi523,Ca(2+)-S100B
分子名称: CALCIUM ION, Protein S100-B, ethyl 5-{[(1R)-1-(ethoxycarbonyl)-2-oxopropyl]sulfanyl}-1,2-dihydro[1,2,3]triazolo[1,5-a]quinazoline-3-carboxylate
著者Charpentier, T.H, Weber, D.J, Toth, E.A.
登録日2009-03-09
公開日2009-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Small molecules bound to unique sites in the target protein binding cleft of calcium-bound S100B as characterized by nuclear magnetic resonance and X-ray crystallography.
Biochemistry, 48, 2009
3GK1
DownloadVisualize
BU of 3gk1 by Molmil
X-ray structure of bovine SBi132,Ca(2+)-S100B
分子名称: 2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide, CACODYLATE ION, CALCIUM ION, ...
著者Charpentier, T.H, Weber, D.J, Toth, E.A.
登録日2009-03-09
公開日2009-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Small molecules bound to unique sites in the target protein binding cleft of calcium-bound S100B as characterized by nuclear magnetic resonance and X-ray crystallography.
Biochemistry, 48, 2009
3IQQ
DownloadVisualize
BU of 3iqq by Molmil
X-ray structure of bovine TRTK12-Ca(2+)-S100B
分子名称: CALCIUM ION, Protein S100-B, TRTK12 peptide, ...
著者Charpentier, T.H, Weber, D.J, Toth, E.A.
登録日2009-08-20
公開日2010-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献The Effects of CapZ Peptide (TRTK-12) Binding to S100B-Ca(2+) as Examined by NMR and X-ray Crystallography
J.Mol.Biol., 396, 2010
3IQO
DownloadVisualize
BU of 3iqo by Molmil
1.5 angstrom X-ray structure of bovine Ca(2+)-S100B
分子名称: CALCIUM ION, Protein S100-B
著者Charpentier, T.H, Weber, D.J, Toth, E.A.
登録日2009-08-20
公開日2010-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The Effects of CapZ Peptide (TRTK-12) Binding to S100B-Ca(2+) as Examined by NMR and X-ray Crystallography
J.Mol.Biol., 396, 2010

 

12>

220113

件を2024-05-22に公開中

PDB statisticsPDBj update infoContact PDBjnumon