6U9L

Imidazole-triggered RAS-specific subtilisin SUBT_BACAM

Summary for 6U9L

Entry DOI	10.2210/pdb6u9l/pdb
Descriptor	SUBTILISIN BPN', POTASSIUM ION, GLYCEROL, ... (5 entities in total)
Functional Keywords	engineered protease, hydrolase
Biological source	Bacillus amyloliquefaciens
Total number of polymer chains	1
Total formula weight	26956.32
Authors	Toth, E.A.,Bryan, P.N.,Orban, J. (deposition date: 2019-09-09, release date: 2020-09-16, Last modification date: 2023-10-11)
Primary citation	Chen, Y.,Toth, E.A.,Ruan, B.,Choi, E.J.,Simmerman, R.,Chen, Y.,He, Y.,Wang, R.,Godoy-Ruiz, R.,King, H.,Custer, G.,Travis Gallagher, D.,Rozak, D.A.,Solomon, M.,Muro, S.,Weber, D.J.,Orban, J.,Fuerst, T.R.,Bryan, P.N. Engineering subtilisin proteases that specifically degrade active RAS. Commun Biol, 4:299-299, 2021 Cited by PubMed: 33674772 DOI: 10.1038/s42003-021-01818-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation