6U9L
Imidazole-triggered RAS-specific subtilisin SUBT_BACAM
Summary for 6U9L
Entry DOI | 10.2210/pdb6u9l/pdb |
Descriptor | SUBTILISIN BPN', POTASSIUM ION, GLYCEROL, ... (5 entities in total) |
Functional Keywords | engineered protease, hydrolase |
Biological source | Bacillus amyloliquefaciens |
Total number of polymer chains | 1 |
Total formula weight | 26956.32 |
Authors | Toth, E.A.,Bryan, P.N.,Orban, J. (deposition date: 2019-09-09, release date: 2020-09-16, Last modification date: 2023-10-11) |
Primary citation | Chen, Y.,Toth, E.A.,Ruan, B.,Choi, E.J.,Simmerman, R.,Chen, Y.,He, Y.,Wang, R.,Godoy-Ruiz, R.,King, H.,Custer, G.,Travis Gallagher, D.,Rozak, D.A.,Solomon, M.,Muro, S.,Weber, D.J.,Orban, J.,Fuerst, T.R.,Bryan, P.N. Engineering subtilisin proteases that specifically degrade active RAS. Commun Biol, 4:299-299, 2021 Cited by PubMed: 33674772DOI: 10.1038/s42003-021-01818-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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