6UBE

Azide-triggered subtilisin SUBT_BACAM complexed with the peptide LFRAL

Summary for 6UBE

Entry DOI	10.2210/pdb6ube/pdb
Related	6U9L 6UAI 6UAO
Descriptor	SUBTILISIN BPN', Peptide LFRAL, SODIUM ION, ... (6 entities in total)
Functional Keywords	engineered protease, hydrolase
Biological source	Bacillus amyloliquefaciens More
Total number of polymer chains	2
Total formula weight	27547.59
Authors	Toth, E.A.,Bryan, P.N.,Orban, J.,Gallagher, D.T.,Custer, G. (deposition date: 2019-09-11, release date: 2020-09-16, Last modification date: 2023-10-11)
Primary citation	Chen, Y.,Toth, E.A.,Ruan, B.,Choi, E.J.,Simmerman, R.,Chen, Y.,He, Y.,Wang, R.,Godoy-Ruiz, R.,King, H.,Custer, G.,Travis Gallagher, D.,Rozak, D.A.,Solomon, M.,Muro, S.,Weber, D.J.,Orban, J.,Fuerst, T.R.,Bryan, P.N. Engineering subtilisin proteases that specifically degrade active RAS. Commun Biol, 4:299-299, 2021 Cited by PubMed: 33674772 DOI: 10.1038/s42003-021-01818-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation