5EA2

Crystal Structure of Holo NAD(P)H dehydrogenase, quinone 1

Summary for 5EA2

Entry DOI	10.2210/pdb5ea2/pdb
Related	5EAI
Descriptor	NAD(P)H dehydrogenase [quinone] 1, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total)
Functional Keywords	nqo1, two-electron reduction of quinone, nad(p)h dehydrogenase, oxidoreductase
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm: P15559
Total number of polymer chains	4
Total formula weight	127425.17
Authors	Pidugu, L.S.,Mbimba, J.E.,Ahmad, M.,Pozharski, E.,Sausville, E.A.,Emadi, A.,Toth, E.A. (deposition date: 2015-10-15, release date: 2016-02-10, Last modification date: 2023-09-27)
Primary citation	Pidugu, L.S.,Mbimba, J.C.,Ahmad, M.,Pozharski, E.,Sausville, E.A.,Emadi, A.,Toth, E.A. A direct interaction between NQO1 and a chemotherapeutic dimeric naphthoquinone. Bmc Struct.Biol., 16:1-1, 2016 Cited by PubMed: 26822308 DOI: 10.1186/s12900-016-0052-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.01 Å)

Structure validation