4LPY
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![BU of 4lpy by Molmil](/molmil-images/mine/4lpy) | |
4LPV
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![BU of 4lpv by Molmil](/molmil-images/mine/4lpv) | Crystal structure of TENCON variant P41BR3-42 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, TENCON variant P41BR3-42 | Authors: | Teplyakov, A, Obmolova, G, Luo, J, Gilliland, G.L. | Deposit date: | 2013-07-16 | Release date: | 2014-01-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | C-terminal beta-strand swapping in a consensus-derived fibronectin Type III scaffold. Proteins, 82, 2014
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1FL9
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![BU of 1fl9 by Molmil](/molmil-images/mine/1fl9) | THE YJEE PROTEIN | Descriptor: | HYPOTHETICAL PROTEIN HI0065, MERCURY (II) ION | Authors: | Teplyakov, A, Gilliland, G.L, Structure 2 Function Project (S2F) | Deposit date: | 2000-08-13 | Release date: | 2002-08-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the YjeE protein from Haemophilus influenzae: a putative Atpase involved in cell wall synthesis Proteins, 48, 2002
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4KMT
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![BU of 4kmt by Molmil](/molmil-images/mine/4kmt) | Crystal structure of human germline antibody 5-51/O12 | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, SULFATE ION, ... | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | Deposit date: | 2013-05-08 | Release date: | 2014-03-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Antibody modeling assessment II. Structures and models. Proteins, 82, 2014
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4KQ4
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![BU of 4kq4 by Molmil](/molmil-images/mine/4kq4) | Crystal structure of Anti-IL-17A antibody CNTO7357 | Descriptor: | CNTO7357 heavy chain, CNTO7357 light chain, NICKEL (II) ION | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | Deposit date: | 2013-05-14 | Release date: | 2014-03-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Antibody modeling assessment II. Structures and models. Proteins, 82, 2014
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4M7K
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![BU of 4m7k by Molmil](/molmil-images/mine/4m7k) | Crystal structure of anti-tissue factor antibody 10H10 | Descriptor: | 10H10 heavy chain, 10H10 light chain, ACETATE ION, ... | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | Deposit date: | 2013-08-12 | Release date: | 2014-03-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Antibody modeling assessment II. Structures and models. Proteins, 82, 2014
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4M6M
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![BU of 4m6m by Molmil](/molmil-images/mine/4m6m) | Crystal structure of anti-IL-23 antibody CNTO1959 at pH 9.5 | Descriptor: | CNTO1959 heavy chain, CNTO1959 light chain, DI(HYDROXYETHYL)ETHER, ... | Authors: | Teplyakov, A, Obmolova, G, Gilliland, G.L. | Deposit date: | 2013-08-09 | Release date: | 2014-03-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Antibody modeling assessment II. Structures and models. Proteins, 82, 2014
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4M6N
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4L4J
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![BU of 4l4j by Molmil](/molmil-images/mine/4l4j) | Crystal structure of fc-fragment of human IgG2-Sigma antibody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | Authors: | Teplyakov, A, Malia, T, Gillilang, G. | Deposit date: | 2013-06-07 | Release date: | 2013-08-28 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations. Methods, 65, 2014
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4KUZ
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4KQ3
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![BU of 4kq3 by Molmil](/molmil-images/mine/4kq3) | Crystal structure of Anti-IL-17A antibody CNTO3186 | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CNTO3186 heavy chain, ... | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | Deposit date: | 2013-05-14 | Release date: | 2014-03-26 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structural evidence for a constrained conformation of short CDR-L3 in antibodies. Proteins, 82, 2014
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4MAU
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![BU of 4mau by Molmil](/molmil-images/mine/4mau) | Crystal structure of anti-ST2L antibody C2244 | Descriptor: | C2244 heavy chain, C2244 light chain, FORMIC ACID, ... | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | Deposit date: | 2013-08-16 | Release date: | 2014-03-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Antibody modeling assessment II. Structures and models. Proteins, 82, 2014
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4M6O
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![BU of 4m6o by Molmil](/molmil-images/mine/4m6o) | Crystal structure of anti-NGF antibody CNTO7309 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CNTO7309 heavy chain, CNTO7309 light chain, ... | Authors: | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | Deposit date: | 2013-08-09 | Release date: | 2014-03-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Antibody modeling assessment II. Structures and models. Proteins, 82, 2014
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4M7L
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3ULS
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![BU of 3uls by Molmil](/molmil-images/mine/3uls) | Crystal structure of Fab12 | Descriptor: | Fab12 heavy chain, Fab12 light chain | Authors: | Luo, J, Gilliland, G.L, Obmolova, O, Malia, T, Teplyakov, A. | Deposit date: | 2011-11-11 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.495 Å) | Cite: | Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure. J.Mol.Biol., 421, 2012
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3ULU
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![BU of 3ulu by Molmil](/molmil-images/mine/3ulu) | Structure of quaternary complex of human TLR3ecd with three Fabs (Form1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab1068 heavy chain, ... | Authors: | Luo, J, Gilliland, G.L, Obmolova, O, Malia, T, Teplyakov, A. | Deposit date: | 2011-11-11 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.52 Å) | Cite: | Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure. J.Mol.Biol., 421, 2012
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6XLI
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![BU of 6xli by Molmil](/molmil-images/mine/6xli) | CRYSTAL STRUCTURE OF ANTI-TAU ANTIBODY PT3 Fab+pT212/pT217-TAU PEPTIDE | Descriptor: | GLYCEROL, PT3 Fab Heavy Chain, PT3 Fab Light Chain, ... | Authors: | Malia, T.J, Teplyakov, A, Luo, J. | Deposit date: | 2020-06-28 | Release date: | 2020-09-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery and Functional Characterization of hPT3, a Humanized Anti-Phospho Tau Selective Monoclonal Antibody. J Alzheimers Dis, 77, 2020
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1B7D
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![BU of 1b7d by Molmil](/molmil-images/mine/1b7d) | NEUROTOXIN (TS1) FROM BRAZILIAN SCORPION TITYUS SERRULATUS | Descriptor: | PHOSPHATE ION, PROTEIN (NEUROTOXIN TS1) | Authors: | Polikarpov, I, Sanches Jr, M.S, Marangoni, S, Toyama, M.H, Teplyakov, A. | Deposit date: | 1999-01-21 | Release date: | 1999-07-22 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Crystal structure of neurotoxin Ts1 from Tityus serrulatus provides insights into the specificity and toxicity of scorpion toxins. J.Mol.Biol., 290, 1999
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3ULV
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![BU of 3ulv by Molmil](/molmil-images/mine/3ulv) | Structure of quaternary complex of human TLR3ecd with three Fabs (Form2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab1068 heavy chain, ... | Authors: | Luo, J, Gilliland, G.L, Obmolova, O, Malia, T, Teplyakov, A. | Deposit date: | 2011-11-11 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.522 Å) | Cite: | Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure. J.Mol.Biol., 421, 2012
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2HWG
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![BU of 2hwg by Molmil](/molmil-images/mine/2hwg) | Structure of phosphorylated Enzyme I of the phosphoenolpyruvate:sugar phosphotransferase system | Descriptor: | MAGNESIUM ION, OXALATE ION, Phosphoenolpyruvate-protein phosphotransferase | Authors: | Lim, K, Teplyakov, A, Herzberg, O. | Deposit date: | 2006-08-01 | Release date: | 2006-11-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of phosphorylated enzyme I, the phosphoenolpyruvate:sugar phosphotransferase system sugar translocation signal protein. Proc.Natl.Acad.Sci.Usa, 103, 2006
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4QHU
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![BU of 4qhu by Molmil](/molmil-images/mine/4qhu) | Crystal Structure of IL-17A/Fab6785 complex | Descriptor: | CHLORIDE ION, Fab6785 heavy chain, Fab6785 light chain, ... | Authors: | Luo, J, Gilliland, G.L, Malia, T, Obmolova, G, Teplyakov, A. | Deposit date: | 2014-05-29 | Release date: | 2015-08-05 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | IL-17A Asymmetry in a Complex with a Neutralizing Antibody Fab6785 Reveals a Potential Mechanism of Receptor Differentiation To be Published
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4DN4
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![BU of 4dn4 by Molmil](/molmil-images/mine/4dn4) | Crystal structure of the complex between cnto888 fab and mcp-1 mutant p8a | Descriptor: | ACETATE ION, C-C motif chemokine 2, CNTO888 HEAVY CHAIN, ... | Authors: | Obmolova, G, Teplyakov, A, Malia, T, Grygiel, T, Sweet, R, Snyder, L, Gilliland, G. | Deposit date: | 2012-02-08 | Release date: | 2012-10-03 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888. Mol.Immunol., 51, 2012
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4DN3
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![BU of 4dn3 by Molmil](/molmil-images/mine/4dn3) | Crystal structure of anti-mcp-1 antibody cnto888 | Descriptor: | CNTO888 HEAVY CHAIN, CNTO888 LIGHT CHAIN | Authors: | Obmolova, G, Teplyakov, A, Malia, T, Grygiel, T, Sweet, R, Snyder, L, Gilliland, G. | Deposit date: | 2012-02-08 | Release date: | 2012-10-03 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888. Mol.Immunol., 51, 2012
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1XFF
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![BU of 1xff by Molmil](/molmil-images/mine/1xff) | Glutaminase domain of glucosamine 6-phosphate synthase complexed with glutamate | Descriptor: | ACETATE ION, GLUTAMIC ACID, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing], ... | Authors: | Isupov, M.N, Teplyakov, A. | Deposit date: | 2004-09-14 | Release date: | 2004-09-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Substrate Binding is Required for Assembly of the Active Conformation of the Catalytic Site in Ntn Amidotransferases: Evidence from the 1.8 Angstrom Crystal Structure of the Glutaminase Domain of Glucosamine 6-Phosphate Synthase Structure, 4, 1996
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1XFG
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![BU of 1xfg by Molmil](/molmil-images/mine/1xfg) | Glutaminase domain of glucosamine 6-phosphate synthase complexed with l-glu hydroxamate | Descriptor: | ACETATE ION, GLUTAMINE HYDROXAMATE, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing], ... | Authors: | Isupov, M.N, Teplyakov, A. | Deposit date: | 2004-09-14 | Release date: | 2004-09-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Substrate Binding is Required for Assembly of the Active Conformation of the Catalytic Site in Ntn Amidotransferases: Evidence from the 1.8 Angstrom Crystal Structure of the Glutaminase Domain of Glucosamine 6-Phosphate Synthase Structure, 4, 1996
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