4QHU
Crystal Structure of IL-17A/Fab6785 complex
Summary for 4QHU
Entry DOI | 10.2210/pdb4qhu/pdb |
Descriptor | Fab6785 light chain, Fab6785 heavy chain, Interleukin-17A, ... (7 entities in total) |
Functional Keywords | antibody-antigen interaction, receptor differentiation, molecular asymmetry, cystine knot, cytokine il-17, il-17ra, il-17rc, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: Q16552 |
Total number of polymer chains | 6 |
Total formula weight | 124652.31 |
Authors | Luo, J.,Gilliland, G.L.,Malia, T.,Obmolova, G.,Teplyakov, A. (deposition date: 2014-05-29, release date: 2015-08-05) |
Primary citation | Luo, J.,Gilliland, G.L.,Malia, T.,Obmolova, G.,Teplyakov, A. IL-17A Asymmetry in a Complex with a Neutralizing Antibody Fab6785 Reveals a Potential Mechanism of Receptor Differentiation To be Published, |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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