3ULU
Structure of quaternary complex of human TLR3ecd with three Fabs (Form1)
Summary for 3ULU
Entry DOI | 10.2210/pdb3ulu/pdb |
Related | 3ULS 3ULV |
Descriptor | Toll-like receptor 3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total) |
Functional Keywords | toll-like receptor-3, tlr3, innate immunity, leucine rich repeat, lrr, immunoglobulin, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 7 |
Total formula weight | 225961.43 |
Authors | Luo, J.,Gilliland, G.L.,Obmolova, O.,Malia, T.,Teplyakov, A. (deposition date: 2011-11-11, release date: 2012-05-23, Last modification date: 2023-09-13) |
Primary citation | Luo, J.,Obmolova, G.,Malia, T.J.,Wu, S.J.,Duffy, K.E.,Marion, J.D.,Bell, J.K.,Ge, P.,Zhou, Z.H.,Teplyakov, A.,Zhao, Y.,Lamb, R.J.,Jordan, J.L.,San Mateo, L.R.,Sweet, R.W.,Gilliland, G.L. Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure. J.Mol.Biol., 421:112-124, 2012 Cited by PubMed: 22579623DOI: 10.1016/j.jmb.2012.05.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.52 Å) |
Structure validation
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