7S4U
 
 | | Cryo-EM structure of Cas9 in complex with 12-14MM DNA substrate, 5 minute time-point | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, Non-target strand, Target strand, ... | | 著者 | Bravo, J.P.K, Taylor, D.W, Liu, M.S, Johnson, K.A. | | 登録日 | 2021-09-09 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.56 Å) | | 主引用文献 | Structural basis for mismatch surveillance by CRISPR-Cas9.
Nature, 603, 2022
|
|
7S4X
 | | Cas9:gRNA in complex with 18-20MM DNA, 1 minute time-point, kinked active conformation | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ... | | 著者 | Bravo, J.P.K, Taylor, D.W, Liu, M.S, Johnson, K.A. | | 登録日 | 2021-09-09 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | Structural basis for mismatch surveillance by CRISPR-Cas9.
Nature, 603, 2022
|
|
7SBB
 | |
7SBA
 | |
7S9V
 | | DrmAB:ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DrmA, DrmB | | 著者 | Bravo, J.P.K, Taylor, D.W, Brouns, S.J.J, Aparicio-Maldonado, C. | | 登録日 | 2021-09-21 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis for broad anti-phage immunity by DISARM.
Nat Commun, 13, 2022
|
|
7S9W
 | | Structure of DrmAB:ADP:DNA complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*T)-3'), DrmA, ... | | 著者 | Bravo, J.P.K, Taylor, D.W, Brounds, S.J.J, Aparicio-Maldonado, C. | | 登録日 | 2021-09-21 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis for broad anti-phage immunity by DISARM.
Nat Commun, 13, 2022
|
|
7S4V
 | | Cas9 bound to 12-14MM DNA, 60 min time-point, kinked conformation | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ... | | 著者 | Bravo, J.P.K, Taylor, D.W, Liu, M.S, Johnson, K.A. | | 登録日 | 2021-09-09 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | Structural basis for mismatch surveillance by CRISPR-Cas9.
Nature, 603, 2022
|
|
8TL0
 | |
8U3Y
 | | SpG Cas9 with NGG PAM DNA target | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(P*CP*GP*TP*TP*TP*GP*TP*AP*CP*TP*CP*CP*AP*GP*CP*G)-3'), DNA (5'-D(P*TP*CP*TP*CP*AP*TP*CP*TP*TP*TP*AP*TP*GP*CP*GP*TP*C)-3'), ... | | 著者 | Bravo, J.P.K, Hibshman, G.N, Taylor, D.W. | | 登録日 | 2023-09-08 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
|
|
8TZZ
 | | SpG Cas9 with NGC PAM DNA target | | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(P*CP*GP*TP*TP*TP*GP*TP*AP*CP*TP*GP*CP*AP*GP*CP*G)-3'), DNA (5'-D(P*TP*CP*TP*CP*AP*TP*CP*TP*TP*TP*AP*TP*GP*CP*GP*TP*C)-3'), ... | | 著者 | Bravo, J.P.K, Hibshman, G.N, Taylor, D.W. | | 登録日 | 2023-08-28 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.56 Å) | | 主引用文献 | Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9.
Nat Commun, 15, 2024
|
|
9BQV
 | | DdmD dimer apoprotein | | 分子名称: | Helicase/UvrB N-terminal domain-containing protein | | 著者 | Bravo, J.P.K, Taylor, D.W. | | 登録日 | 2024-05-10 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Plasmid targeting and destruction by the DdmDE bacterial defence system.
Nature, 630, 2024
|
|
7UG6
 | | Cryo-EM structure of pre-60S ribosomal subunit, unmethylated G2922 | | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Yelland, J.N, Bravo, J.P.K, Black, J.J.B, Taylor, D.W, Johnson, A.W. | | 登録日 | 2022-03-24 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | A single 2'-O-methylation of ribosomal RNA gates assembly of a functional ribosome.
Nat.Struct.Mol.Biol., 30, 2023
|
|
6MDR
 | | Cryo-EM structure of the Ceru+32/GFP-17 protomer | | 分子名称: | Ceru+32, GFP-17 | | 著者 | Simon, A.J, Zhou, Y, Ramasubramani, V, Glaser, J, Pothukuchy, A, Golihar, J, Gerberich, J.C, Leggere, J.C, Morrow, B.R, Jung, C, Glotzer, S.C, Taylor, D.W, Ellington, A.D. | | 登録日 | 2018-09-05 | | 公開日 | 2019-01-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Supercharging enables organized assembly of synthetic biomolecules.
Nat Chem, 11, 2019
|
|
6N8K
 | | Cryo-EM structure of early cytoplasmic-immediate (ECI) pre-60S ribosomal subunit | | 分子名称: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | | 著者 | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | | 登録日 | 2018-11-29 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
|
|
6N8O
 | | Cryo-EM structure of Rpl10-inserted (RI) pre-60S ribosomal subunit | | 分子名称: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | | 著者 | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | | 登録日 | 2018-11-29 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
|
|
6N8J
 | | Cryo-EM structure of late nuclear (LN) pre-60S ribosomal subunit | | 分子名称: | 5.8S rRNA, 5S rRNA, 60S ribosomal protein L11-A, ... | | 著者 | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | | 登録日 | 2018-11-29 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
|
|
6N8L
 | | Cryo-EM structure of early cytoplasmic-late (ECL) pre-60S ribosomal subunit | | 分子名称: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | | 著者 | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | | 登録日 | 2018-11-29 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
|
|
6N8M
 | | Cryo-EM structure of pre-Lsg1 (PL) pre-60S ribosomal subunit | | 分子名称: | 5.8S RNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | | 著者 | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | | 登録日 | 2018-11-29 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
|
|
6N8N
 | | Cryo-EM structure of Lsg1-engaged (LE) pre-60S ribosomal subunit | | 分子名称: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | | 著者 | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | | 登録日 | 2018-11-29 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
|
|
7L1F
 | |
2DFS
 | | 3-D structure of Myosin-V inhibited state | | 分子名称: | Calmodulin, Myosin-5A | | 著者 | Liu, J, Taylor, D.W, Krementsova, E.B, Trybus, K.M, Taylor, K.A. | | 登録日 | 2006-03-03 | | 公開日 | 2006-04-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (24 Å) | | 主引用文献 | Three-dimensional structure of the myosin V inhibited state by cryoelectron tomography
Nature, 442, 2006
|
|
1SJJ
 | |
7JHY
 | | Type IV-B CRISPR Complex | | 分子名称: | Csf2 (Cas7), Csf4 (Cas11), RNA (31-MER) | | 著者 | Bravo, J.P.K, Taylor, D.W. | | 登録日 | 2020-07-21 | | 公開日 | 2021-03-31 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structure of a type IV CRISPR-Cas ribonucleoprotein complex.
Iscience, 24, 2021
|
|
4CMQ
 | | Crystal structure of Mn-bound S.pyogenes Cas9 | | 分子名称: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MANGANESE (II) ION, SULFATE ION | | 著者 | Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A. | | 登録日 | 2014-01-17 | | 公開日 | 2014-02-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | | 主引用文献 | Structures of Cas9 Endonucleases Reveal RNA- Mediated Conformational Activation
Science, 343, 2014
|
|
4CMP
 | | Crystal structure of S. pyogenes Cas9 | | 分子名称: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, SULFATE ION | | 著者 | Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A. | | 登録日 | 2014-01-16 | | 公開日 | 2014-02-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation.
Science, 343, 2014
|
|
