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PDB: 194 件
1Y0V
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BU of 1y0v by Molmil
Crystal structure of anthrax edema factor (EF) in complex with calmodulin and pyrophosphate
分子名称: CALCIUM ION, Calmodulin, Calmodulin-sensitive adenylate cyclase, ...
著者Shen, Y, Zhukovskaya, N.L, Guo, Q, Florian, J, Tang, W.-J.
登録日2004-11-16
公開日2005-05-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor
Embo J., 24, 2005
1XFY
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BU of 1xfy by Molmil
Crystal structure of anthrax edema factor (EF) in complex with calmodulin
分子名称: CALCIUM ION, Calmodulin 2, Calmodulin-sensitive adenylate cyclase, ...
著者Shen, Y, Zhukovskaya, N.L, Guo, Q, Florian, J, Tang, W.J.
登録日2004-09-15
公開日2005-05-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
EMBO J., 24, 2005
4KOD
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BU of 4kod by Molmil
Structure of p97 N-D1 R155H mutant in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
著者Xia, D, Tang, W.K.
登録日2013-05-11
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants.
J.Biol.Chem., 288, 2013
1XFX
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BU of 1xfx by Molmil
Crystal structure of anthrax edema factor (EF) in complex with calmodulin in the presence of 10 millimolar exogenously added calcium chloride
分子名称: CALCIUM ION, Calmodulin 2, Calmodulin-sensitive adenylate cyclase, ...
著者Shen, Y, Zhukovskaya, N.L, Guo, Q, Florian, J, Tang, W.J.
登録日2004-09-15
公開日2005-05-03
最終更新日2017-12-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
EMBO J., 24, 2005
1XFW
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BU of 1xfw by Molmil
Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3'5' cyclic AMP (cAMP)
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CALCIUM ION, Calmodulin 2, ...
著者Shen, Y, Zhukovskaya, N.L, Guo, Q, Florian, J, Tang, W.J.
登録日2004-09-15
公開日2005-05-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
EMBO J., 24, 2005
4KLN
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BU of 4kln by Molmil
Structure of p97 N-D1 A232E mutant in complex with ATPgS
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Xia, D, Tang, W.K.
登録日2013-05-07
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants.
J.Biol.Chem., 288, 2013
1XFV
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BU of 1xfv by Molmil
Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP
分子名称: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin 2, ...
著者Shen, Q, Zhukovskaya, N.L, Guo, Q, Florian, J, Tang, W.J.
登録日2004-09-15
公開日2005-05-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.
EMBO J., 24, 2005
1K8T
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BU of 1k8t by Molmil
Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF)
分子名称: CALMODULIN-SENSITIVE ADENYLATE CYCLASE, NICKEL (II) ION, SULFATE ION
著者Drum, C.L, Yan, S.-Z, Bard, J, Shen, Y.-Q, Lu, D, Soelaiman, S, Grabarek, Z, Bohm, A, Tang, W.-J.
登録日2001-10-25
公開日2002-01-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin
Nature, 415, 2002
8TWF
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BU of 8twf by Molmil
Crystal structure of tetracycline destructase Tet(56-3)
分子名称: 6-hydroxynicotinate 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE
著者Kumar, H, Tang, W.K, Tolia, N.
登録日2023-08-21
公開日2024-07-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes.
Commun Biol, 7, 2024
3H44
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BU of 3h44 by Molmil
Crystal Structure of Insulin Degrading Enzyme in Complex with macrophage inflammatory protein 1 alpha
分子名称: 1,4-DIETHYLENE DIOXIDE, C-C motif chemokine 3, Insulin-degrading enzyme, ...
著者Ren, M, Guo, Q, Tang, W.J.
登録日2009-04-17
公開日2010-04-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Macrophage Inflammatory Protein-1 Is A Novel High Affinity Substrate For Human Insulin Degrading Enzyme
To be Published
3HGZ
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BU of 3hgz by Molmil
Crystal structure of human insulin-degrading enzyme in complex with amylin
分子名称: Insulin-degrading enzyme, Islet amyloid polypeptide, ZINC ION
著者Guo, Q, Bian, Y, Tang, W.J.
登録日2009-05-14
公開日2009-12-08
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-alpha, and Amylin by Human Insulin-Degrading Enzyme.
J.Mol.Biol., 395, 2010
3TN2
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BU of 3tn2 by Molmil
structure analysis of MIP1-beta P8A
分子名称: C-C motif chemokine 4, ZINC ION
著者Guo, Q, Tang, W.J.
登録日2011-09-01
公開日2012-09-05
最終更新日2018-08-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme.
J.Mol.Biol., 427, 2015
1FI9
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BU of 1fi9 by Molmil
SOLUTION STRUCTURE OF THE IMIDAZOLE COMPLEX OF CYTOCHROME C
分子名称: CYTOCHROME C, HEME C, IMIDAZOLE
著者Banci, L, Bertini, I, Liu, G, Lu, J, Reddig, T, Tang, W, Wu, Y, Zhu, D.
登録日2000-08-03
公開日2000-08-23
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Effects of extrinsic imidazole ligation on the molecular and electronic structure of cytochrome c
J.Biol.Inorg.Chem., 6, 2001
8TWG
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BU of 8twg by Molmil
Crystal structure of tetracycline destructase Tet(56-2)
分子名称: 6-hydroxynicotinate 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE
著者Kumar, H, Tang, W.K, Tolia, N.
登録日2023-08-21
公開日2024-07-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes.
Commun Biol, 7, 2024
4L3T
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BU of 4l3t by Molmil
Crystal Structure of Substrate-free Human Presequence Protease
分子名称: ACETATE ION, GLYCEROL, Presequence protease, ...
著者King, J.V, Liang, W.G, Tang, W.J.
登録日2013-06-06
公開日2013-07-03
最終更新日2014-07-23
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Molecular basis of substrate recognition and degradation by human presequence protease.
Structure, 22, 2014
1FI7
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BU of 1fi7 by Molmil
Solution structure of the imidazole complex of cytochrome C
分子名称: CYTOCHROME C, HEME C, IMIDAZOLE
著者Banci, L, Bertini, I, Liu, G, Lu, J, Reddig, T, Tang, W, Wu, Y, Zhu, D.
登録日2000-08-03
公開日2000-08-23
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Effects of extrinsic imidazole ligation on the molecular and electronic structure of cytochrome c
J.Biol.Inorg.Chem., 6, 2001
1I5T
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BU of 1i5t by Molmil
SOLUTION STRUCTURE OF CYANOFERRICYTOCHROME C
分子名称: CYANIDE ION, CYTOCHROME C, HEME C
著者Yao, Y, Qian, C, Ye, K, Wang, J, Tang, W.
登録日2001-02-28
公開日2001-03-21
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of cyanoferricytochrome c: ligand-controlled conformational flexibility and electronic structure of the heme moiety.
J.Biol.Inorg.Chem., 7, 2002
1K93
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BU of 1k93 by Molmil
Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin
分子名称: CALCIUM ION, CALMODULIN, CALMODULIN-SENSITIVE ADENYLATE CYCLASE, ...
著者Drum, C.L, Yan, S.-Z, Bard, J, Shen, Y.-Q, Lu, D, Soelaiman, S, Grabarek, Z, Bohm, A, Tang, W.-J.
登録日2001-10-26
公開日2002-01-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin.
Nature, 415, 2002
1YRT
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BU of 1yrt by Molmil
Crystal Structure analysis of the adenylyl cyclaes catalytic domain of adenylyl cyclase toxin of Bordetella pertussis in presence of c-terminal calmodulin
分子名称: Bifunctional hemolysin-adenylate cyclase, CALCIUM ION, Calmodulin
著者Guo, Q, Shen, Y, Lee, Y.S, Gibbs, C.S, Mrksich, M, Tang, W.J.
登録日2005-02-04
公開日2006-01-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin.
Embo J., 24, 2005
1YRU
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BU of 1yru by Molmil
Crystal Structure analysis of the adenylyl cyclaes catalytic domain of adenylyl cyclase toxin of Bordetella pertussis in presence of c-terminal calmodulin and 1mM calcium chloride
分子名称: Bifunctional hemolysin-adenylate cyclase, CALCIUM ION, Calmodulin
著者Guo, Q, Shen, Y, Tang, W.J.
登録日2005-02-04
公開日2005-09-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin
Embo J., 24, 2005
1M60
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BU of 1m60 by Molmil
Solution Structure of Zinc-substituted cytochrome c
分子名称: ZINC SUBSTITUTED HEME C, Zinc-substituted cytochrome c
著者Qian, C, Yao, Y, Tong, Y, Wang, J, Tang, W.
登録日2002-07-11
公開日2002-08-07
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Structural analysis of zinc-substituted cytochrome c.
J.Biol.Inorg.Chem., 8, 2003
4NGE
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BU of 4nge by Molmil
Crystal Structure of Human Presequence Protease in Complex with Amyloid-beta (1-40)
分子名称: ACETATE ION, Beta-amyloid protein 40, GLYCEROL, ...
著者King, J.V, Liang, W.G, Tang, W.J.
登録日2013-11-01
公開日2014-05-14
最終更新日2014-07-23
実験手法X-RAY DIFFRACTION (2.704 Å)
主引用文献Molecular basis of substrate recognition and degradation by human presequence protease.
Structure, 22, 2014
4GSC
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BU of 4gsc by Molmil
Structure analysis of insulin degrading enzyme with compound bdm41559 ((s)-2-[2-(carboxymethyl-phenethyl-amino)-acetylamino]-3-(1h-imidazol-4-yl)-propionic acid methyl ester)
分子名称: Insulin-degrading enzyme, ZINC ION, methyl N-(carboxymethyl)-N-(2-phenylethyl)glycyl-L-histidinate
著者Guo, Q, Deprez-Poulain, R, Deprez, B, Tang, W.J.
登録日2012-08-27
公開日2013-08-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-beta hydrolysis.
Eur.J.Med.Chem., 79, 2014
1ZOT
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crystal structure analysis of the CyaA/C-Cam with PMEAPP
分子名称: (ADENIN-9-YL-ETHOXYMETHYL)-HYDROXYPHOSPHINYL-DIPHOSPHATE, CALCIUM ION, Calmodulin, ...
著者Guo, Q, Tang, W.J.
登録日2005-05-13
公開日2005-08-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin.
Embo J., 24, 2005
4KO8
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BU of 4ko8 by Molmil
Structure of p97 N-D1 R155H mutant in complex with ATPgS
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Xia, D, Tang, W.K.
登録日2013-05-11
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants.
J.Biol.Chem., 288, 2013

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