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PDB: 189 件

5KKZ
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Rhodobacter sphaeroides bc1 with famoxadone
分子名称: (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, ASCORBIC ACID, Cytochrome b, ...
著者Xia, D, Esser, L, Zhou, F, Tang, W.K, Yu, C.A.
登録日2016-06-23
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III.
J.Biol.Chem., 291, 2016
2PQ3
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N-Terminal Calmodulin Zn-Trapped Intermediate
分子名称: CACODYLATE ION, Calmodulin, ZINC ION
著者Warren, J.T, Guo, Q, Tang, W.J.
登録日2007-05-01
公開日2007-10-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献A 1.3-A structure of zinc-bound N-terminal domain of calmodulin elucidates potential early ion-binding step.
J.Mol.Biol., 374, 2007
1SK6
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Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin, 3',5' cyclic AMP (cAMP), and pyrophosphate
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CALCIUM ION, Calmodulin, ...
著者Guo, Q, Shen, Y, Zhukovskaya, N.L, Tang, W.J.
登録日2004-03-04
公開日2004-06-08
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural and kinetic analyses of the interaction of anthrax adenylyl cyclase toxin with reaction products cAMP and pyrophosphate.
J.Biol.Chem., 279, 2004
3TN2
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structure analysis of MIP1-beta P8A
分子名称: C-C motif chemokine 4, ZINC ION
著者Guo, Q, Tang, W.J.
登録日2011-09-01
公開日2012-09-05
最終更新日2018-08-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme.
J.Mol.Biol., 427, 2015
4NGE
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Crystal Structure of Human Presequence Protease in Complex with Amyloid-beta (1-40)
分子名称: ACETATE ION, Beta-amyloid protein 40, GLYCEROL, ...
著者King, J.V, Liang, W.G, Tang, W.J.
登録日2013-11-01
公開日2014-05-14
最終更新日2014-07-23
実験手法X-RAY DIFFRACTION (2.704 Å)
主引用文献Molecular basis of substrate recognition and degradation by human presequence protease.
Structure, 22, 2014
3CWW
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Crystal Structure of IDE-bradykinin complex
分子名称: 1,4-DIETHYLENE DIOXIDE, ACETATE ION, Insulin-degrading enzyme, ...
著者Malito, E, Tang, W.J.
登録日2008-04-23
公開日2008-11-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Molecular Bases for the Recognition of Short Peptide Substrates and Cysteine-Directed Modifications of Human Insulin-Degrading Enzyme
Biochemistry, 47, 2008
4L3T
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Crystal Structure of Substrate-free Human Presequence Protease
分子名称: ACETATE ION, GLYCEROL, Presequence protease, ...
著者King, J.V, Liang, W.G, Tang, W.J.
登録日2013-06-06
公開日2013-07-03
最終更新日2014-07-23
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Molecular basis of substrate recognition and degradation by human presequence protease.
Structure, 22, 2014
1NMJ
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The Solution Structure of Rat Ab-(1-28) and its Interaction with Zinc: Insights into the Scarity of Amyloid Deposition in Aged Rat Brain
分子名称: amyloid beta-peptide from Alzheimer's disease amyloid A4 protein homolog
著者Huang, J, Yao, Y, Tang, W.X.
登録日2003-01-10
公開日2003-01-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The solution structure of rat Abeta-(1-28) and its interaction with zinc ion: insights into the scarcity of amyloid deposition in aged rat brain
J.Biol.Inorg.Chem., 9, 2004
4QIA
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Crystal structure of human insulin degrading enzyme (ide) in complex with inhibitor N-benzyl-N-(carboxymethyl)glycyl-L-histidine
分子名称: Insulin-degrading enzyme, N-benzyl-N-(carboxymethyl)glycyl-L-histidine, ZINC ION
著者Guo, Q, Deprez-Poulain, R, Deprez, B, Tang, W.J.
登録日2014-05-30
公開日2015-05-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.202 Å)
主引用文献Structure-activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human insulin-degrading enzyme.
Eur.J.Med.Chem., 90, 2015
5CJO
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Crystal Structure Analysis of Elbow-Engineered-Fab-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Insulin
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FAB Heavy chain with engineered elbow, FAB light chain, ...
著者liang, w.g, bailey, L, tang, w.j.
登録日2015-07-14
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.287 Å)
主引用文献Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.
J. Mol. Biol., 2017
4IOF
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Crystal structure analysis of Fab-bound human Insulin Degrading Enzyme (IDE)
分子名称: Fab-bound IDE, heavy chain, light chain, ...
著者McCord, L.A, Liang, W.G, Hoey, R, Dowdell, E, Koide, A, Koide, S, Tang, W.J.
登録日2013-01-07
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.353 Å)
主引用文献Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme.
Proc.Natl.Acad.Sci.USA, 110, 2013
5C6R
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Crystal structure of PH domain of ASAP1
分子名称: Arf-GAP, PHOSPHATE ION, TRIETHYLENE GLYCOL
著者Xia, D, Tang, W.K.
登録日2015-06-23
公開日2015-10-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular Basis for Cooperative Binding of Anionic Phospholipids to the PH Domain of the Arf GAP ASAP1.
Structure, 23, 2015
1I5T
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SOLUTION STRUCTURE OF CYANOFERRICYTOCHROME C
分子名称: CYANIDE ION, CYTOCHROME C, HEME C
著者Yao, Y, Qian, C, Ye, K, Wang, J, Tang, W.
登録日2001-02-28
公開日2001-03-21
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of cyanoferricytochrome c: ligand-controlled conformational flexibility and electronic structure of the heme moiety.
J.Biol.Inorg.Chem., 7, 2002
1FI9
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SOLUTION STRUCTURE OF THE IMIDAZOLE COMPLEX OF CYTOCHROME C
分子名称: CYTOCHROME C, HEME C, IMIDAZOLE
著者Banci, L, Bertini, I, Liu, G, Lu, J, Reddig, T, Tang, W, Wu, Y, Zhu, D.
登録日2000-08-03
公開日2000-08-23
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Effects of extrinsic imidazole ligation on the molecular and electronic structure of cytochrome c
J.Biol.Inorg.Chem., 6, 2001
5C79
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PH domain of ASAP1 in complex with diC4-PtdIns(4,5)P2
分子名称: (2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1 ,2-DIYL DIBUTANOATE, Arf-GAP, CHLORIDE ION
著者Xia, D, Tang, W.K.
登録日2015-06-24
公開日2015-10-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular Basis for Cooperative Binding of Anionic Phospholipids to the PH Domain of the Arf GAP ASAP1.
Structure, 23, 2015
1FI7
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BU of 1fi7 by Molmil
Solution structure of the imidazole complex of cytochrome C
分子名称: CYTOCHROME C, HEME C, IMIDAZOLE
著者Banci, L, Bertini, I, Liu, G, Lu, J, Reddig, T, Tang, W, Wu, Y, Zhu, D.
登録日2000-08-03
公開日2000-08-23
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Effects of extrinsic imidazole ligation on the molecular and electronic structure of cytochrome c
J.Biol.Inorg.Chem., 6, 2001
3HGZ
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BU of 3hgz by Molmil
Crystal structure of human insulin-degrading enzyme in complex with amylin
分子名称: Insulin-degrading enzyme, Islet amyloid polypeptide, ZINC ION
著者Guo, Q, Bian, Y, Tang, W.J.
登録日2009-05-14
公開日2009-12-08
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-alpha, and Amylin by Human Insulin-Degrading Enzyme.
J.Mol.Biol., 395, 2010
4KLN
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BU of 4kln by Molmil
Structure of p97 N-D1 A232E mutant in complex with ATPgS
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Xia, D, Tang, W.K.
登録日2013-05-07
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants.
J.Biol.Chem., 288, 2013
4KOD
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Structure of p97 N-D1 R155H mutant in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
著者Xia, D, Tang, W.K.
登録日2013-05-11
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants.
J.Biol.Chem., 288, 2013
3H44
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Crystal Structure of Insulin Degrading Enzyme in Complex with macrophage inflammatory protein 1 alpha
分子名称: 1,4-DIETHYLENE DIOXIDE, C-C motif chemokine 3, Insulin-degrading enzyme, ...
著者Ren, M, Guo, Q, Tang, W.J.
登録日2009-04-17
公開日2010-04-14
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Macrophage Inflammatory Protein-1 Is A Novel High Affinity Substrate For Human Insulin Degrading Enzyme
To be Published
3QZ2
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The structure of cysteine-free human insulin degrading enzyme
分子名称: Insulin-degrading enzyme, ZINC ION
著者Guo, Q, Tang, W.J.
登録日2011-03-04
公開日2012-01-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-beta hydrolysis.
Eur.J.Med.Chem., 79, 2014
4GSF
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BU of 4gsf by Molmil
The structure analysis of cysteine free insulin degrading enzyme (ide) with (s)-2-{2-[carboxymethyl-(3-phenyl-propionyl)-amino]-acetylamino}-3-(3h-imidazol-4-yl)-propionic acid methyl ester
分子名称: Insulin-degrading enzyme, ZINC ION, methyl N-(carboxymethyl)-N-(3-phenylpropanoyl)glycyl-D-histidinate
著者Guo, Q, Deprez-Poulain, R, Deprez, B, Tang, W.J.
登録日2012-08-27
公開日2013-08-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure-activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human insulin-degrading enzyme.
Eur.J.Med.Chem., 90, 2015
4F33
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Crystal Structure of therapeutic antibody MORAb-009
分子名称: MORAb-009 FAB heavy chain, MORAb-009 FAB light chain, TETRAETHYLENE GLYCOL
著者Xia, D, Ma, J, Tang, W.K, Esser, L.
登録日2012-05-08
公開日2012-07-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.749 Å)
主引用文献Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights.
J.Biol.Chem., 287, 2012
1M60
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Solution Structure of Zinc-substituted cytochrome c
分子名称: ZINC SUBSTITUTED HEME C, Zinc-substituted cytochrome c
著者Qian, C, Yao, Y, Tong, Y, Wang, J, Tang, W.
登録日2002-07-11
公開日2002-08-07
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Structural analysis of zinc-substituted cytochrome c.
J.Biol.Inorg.Chem., 8, 2003
1NMI
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Solution structure of the imidazole complex of iso-1 cytochrome c
分子名称: Cytochrome c, iso-1, HEME C, ...
著者Yao, Y, Tong, Y, Liu, G, Wang, J, Zheng, J, Tang, W.
登録日2003-01-10
公開日2003-02-04
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of the imidazole complex of iso-1 cytochrome c
To be Published

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