8P30
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![BU of 8p30 by Molmil](/molmil-images/mine/8p30) | Structure of human SIT1:ACE2 complex (open PD conformation) bound to L-pipecolate | Descriptor: | (2S)-piperidine-2-carboxylic acid, 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | Deposit date: | 2023-05-16 | Release date: | 2024-06-12 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.29 Å) | Cite: | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
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2J8T
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![BU of 2j8t by Molmil](/molmil-images/mine/2j8t) | Human aldose reductase in complex with NADP and citrate at 0.82 angstrom | Descriptor: | ALDO-KETO REDUCTASE FAMILY 1, MEMBER B1, CITRATE ANION, ... | Authors: | Biadene, M, Hazemann, I, Cousido, A, Ginell, S, Sheldrick, G.M, Podjarny, A, Schneider, T.R. | Deposit date: | 2006-10-27 | Release date: | 2007-05-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (0.82 Å) | Cite: | The Atomic Resolution Structure of Human Aldose Reductase Reveals that Rearrangement of a Bound Ligand Allows the Opening of the Safety-Belt Loop. Acta Crystallogr.,Sect.D, 63, 2007
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8P31
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![BU of 8p31 by Molmil](/molmil-images/mine/8p31) | Structure of human SIT1:ACE2 complex (closed PD conformation) bound to L-pipecolate | Descriptor: | (2S)-piperidine-2-carboxylic acid, 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | Deposit date: | 2023-05-16 | Release date: | 2024-06-12 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
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8P2X
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![BU of 8p2x by Molmil](/molmil-images/mine/8p2x) | Structure of human SIT1:ACE2 complex (open PD conformation) | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | Deposit date: | 2023-05-16 | Release date: | 2024-06-12 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.59 Å) | Cite: | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
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8P2W
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![BU of 8p2w by Molmil](/molmil-images/mine/8p2w) | Structure of human SIT1 (focussed map / refinement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Sodium- and chloride-dependent transporter XTRP3 | Authors: | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | Deposit date: | 2023-05-16 | Release date: | 2024-06-12 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.76 Å) | Cite: | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
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8P2Y
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![BU of 8p2y by Molmil](/molmil-images/mine/8p2y) | Structure of human SIT1:ACE2 complex (closed PD conformation) | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Li, H.Z, Pike, A.C.W, Chi, G, Hansen, J.S, Lee, S.G, Rodstrom, K.E.J, Bushell, S.R, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Chalk, R, Moreira, T, MacLean, E.M, Marsden, B, Bountra, C, Burgess-Brown, N.A, Dafforn, T.R, Carpenter, E.P, Sauer, D.B. | Deposit date: | 2023-05-16 | Release date: | 2024-06-12 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2. Nat Commun, 15, 2024
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8QO4
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![BU of 8qo4 by Molmil](/molmil-images/mine/8qo4) | Conserved Structures and Dynamics in 5-Proximal Regions of Betacoronavirus RNA Genomes | Descriptor: | MERS-CoV-SL5 | Authors: | Moura, T.R, Purta, E, Bernat, A, Baulin, E, Mukherjee, S, Bujnicki, J.M. | Deposit date: | 2023-09-28 | Release date: | 2024-03-06 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | Conserved structures and dynamics in 5'-proximal regions of Betacoronavirus RNA genomes. Nucleic Acids Res., 52, 2024
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8QO3
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![BU of 8qo3 by Molmil](/molmil-images/mine/8qo3) | Conserved Structures and Dynamics in 5-Proximal Regions of Betacoronavirus RNA Genomes | Descriptor: | RoBat-CoV-SL5 | Authors: | Moura, T.R, Purta, E, Bernat, A, Baulin, E, Mukherjee, S, Bujnicki, J.M. | Deposit date: | 2023-09-28 | Release date: | 2024-03-06 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Conserved structures and dynamics in 5'-proximal regions of Betacoronavirus RNA genomes. Nucleic Acids Res., 52, 2024
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8QQ3
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![BU of 8qq3 by Molmil](/molmil-images/mine/8qq3) | Streptavidin with a Ni-cofactor | Descriptor: | 4-[4-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]butylamino]-~{N}1,~{N}1'-di(quinolin-8-yl)cyclohexane-1,1-dicarboxamide, NICKEL (II) ION, Streptavidin | Authors: | Zhang, K, Jakob, R.P, Ward, T.R. | Deposit date: | 2023-10-03 | Release date: | 2024-02-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | An artificial nickel chlorinase based on the biotin-streptavidin technology. Chem.Commun.(Camb.), 60, 2024
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2I46
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![BU of 2i46 by Molmil](/molmil-images/mine/2i46) | Crystal structure of human TPP1 | Descriptor: | Adrenocortical dysplasia protein homolog | Authors: | Wang, F, Podell, E.R, Zaug, A.J, Yang, Y.T, Baciu, P, Else, T, Hammer, G.D, Cech, T.R, Lei, M. | Deposit date: | 2006-08-21 | Release date: | 2006-11-28 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The POT1-TPP1 telomere complex is a telomerase processivity factor. Nature, 445, 2007
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8QO5
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![BU of 8qo5 by Molmil](/molmil-images/mine/8qo5) | Conserved Structures and Dynamics in 5-Proximal Regions of Betacoronavirus RNA Genomes | Descriptor: | SARS-CoV-2-SL5 | Authors: | Moura, T.R, Purta, E, Bernat, A, Baulin, E, Mukherjee, S, Bujnicki, J.M. | Deposit date: | 2023-09-28 | Release date: | 2024-03-06 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | Conserved structures and dynamics in 5'-proximal regions of Betacoronavirus RNA genomes. Nucleic Acids Res., 52, 2024
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1L2H
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![BU of 1l2h by Molmil](/molmil-images/mine/1l2h) | Crystal structure of Interleukin 1-beta F42W/W120F mutant | Descriptor: | Interleukin 1-beta | Authors: | Rudolph, M.G, Kelker, M.S, Schneider, T.R, Yeates, T.O, Oseroff, V, Heidary, D.K, Jennings, P.A, Wilson, I.A. | Deposit date: | 2002-02-21 | Release date: | 2003-02-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Use of multiple anomalous dispersion to phase highly merohedrally twinned crystals of interleukin-1beta. Acta Crystallogr.,Sect.D, 59, 2003
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2H9T
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![BU of 2h9t by Molmil](/molmil-images/mine/2h9t) | Crystal structure of human alpha-thrombin in complex with suramin | Descriptor: | 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, PPACK active site thrombin inhibitor, Thrombin | Authors: | Lima, L.M.T.R, Polikarpov, I, Monteiro, R.Q. | Deposit date: | 2006-06-11 | Release date: | 2007-05-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural and thermodynamic analysis of thrombin:suramin interaction in solution and crystal phases. Biochim.Biophys.Acta, 1794, 2009
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8QEX
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![BU of 8qex by Molmil](/molmil-images/mine/8qex) | |
2GL1
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![BU of 2gl1 by Molmil](/molmil-images/mine/2gl1) | NMR solution structure of Vigna radiata Defensin 2 (VrD2) | Descriptor: | PDF1 | Authors: | Lin, K.F, Lee, T.R, Tsai, P.H, Hsu, M.P, Chen, C.S, Lyu, P.C. | Deposit date: | 2006-04-04 | Release date: | 2007-04-03 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Structure-based protein engineering for alpha-amylase inhibitory activity of plant defensin. Proteins, 68, 2007
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1I4A
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![BU of 1i4a by Molmil](/molmil-images/mine/1i4a) | CRYSTAL STRUCTURE OF PHOSPHORYLATION-MIMICKING MUTANT T6D OF ANNEXIN IV | Descriptor: | ANNEXIN IV, CALCIUM ION, SULFATE ION | Authors: | Kaetzel, M.A, Mo, Y.D, Mealy, T.R, Campos, B, Bergsma-Schutter, W, Brisson, A, Dedman, J.R, Seaton, B.A. | Deposit date: | 2001-02-20 | Release date: | 2001-04-25 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Phosphorylation mutants elucidate the mechanism of annexin IV-mediated membrane aggregation. Biochemistry, 40, 2001
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2GWR
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![BU of 2gwr by Molmil](/molmil-images/mine/2gwr) | Crystal structure of the response regulator protein mtrA from Mycobacterium Tuberculosis | Descriptor: | CALCIUM ION, DNA-binding response regulator mtrA, GLYCEROL | Authors: | Friedland, N, Mack, T.R, Yu, M, Bursey, E.H, Hung, L.W, Stock, A.M, Waldo, G.S, Terwilliger, T.C. | Deposit date: | 2006-05-05 | Release date: | 2006-05-23 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Domain orientation in the inactive response regulator Mycobacterium tuberculosis MtrA provides a barrier to activation. Biochemistry, 46, 2007
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2GLX
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![BU of 2glx by Molmil](/molmil-images/mine/2glx) | Crystal Structure Analysis of bacterial 1,5-AF Reductase | Descriptor: | 1,5-anhydro-D-fructose reductase, ACETATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Dambe, T.R, Scheidig, A.J. | Deposit date: | 2006-04-05 | Release date: | 2006-08-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of NADP(H)-Dependent 1,5-Anhydro-d-fructose Reductase from Sinorhizobium morelense at 2.2 A Resolution: Construction of a NADH-Accepting Mutant and Its Application in Rare Sugar Synthesis Biochemistry, 45, 2006
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1JLX
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![BU of 1jlx by Molmil](/molmil-images/mine/1jlx) | AGGLUTININ IN COMPLEX WITH T-DISACCHARIDE | Descriptor: | AGGLUTININ, FORMYL GROUP, TOLUENE, ... | Authors: | Transue, T.R, Smith, A.K, Mo, H, Goldstein, I.J, Saper, M.A. | Deposit date: | 1997-07-23 | Release date: | 1997-12-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of benzyl T-antigen disaccharide bound to Amaranthus caudatus agglutinin. Nat.Struct.Biol., 4, 1997
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1JTT
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![BU of 1jtt by Molmil](/molmil-images/mine/1jtt) | Degenerate interfaces in antigen-antibody complexes | Descriptor: | FORMIC ACID, Lysozyme, SODIUM ION, ... | Authors: | Decanniere, K, Transue, T.R, Desmyter, A, Maes, D, Muyldermans, S, Wyns, L. | Deposit date: | 2001-08-22 | Release date: | 2001-12-05 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Degenerate interfaces in antigen-antibody complexes. J.Mol.Biol., 313, 2001
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1JGS
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![BU of 1jgs by Molmil](/molmil-images/mine/1jgs) | Multiple Antibiotic Resistance Repressor, MarR | Descriptor: | 2-HYDROXYBENZOIC ACID, MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN MARR | Authors: | Alekshun, M.N, Levy, S.B, Mealy, T.R, Seaton, B.A, Head, J.F. | Deposit date: | 2001-06-26 | Release date: | 2001-12-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 A resolution. Nat.Struct.Biol., 8, 2001
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1JTO
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![BU of 1jto by Molmil](/molmil-images/mine/1jto) | Degenerate interfaces in antigen-antibody complexes | Descriptor: | Lysozyme, Vh Single-Domain Antibody | Authors: | Decanniere, K, Transue, T.R, Desmyter, A, Maes, D, Muyldermans, S, Wyns, L. | Deposit date: | 2001-08-21 | Release date: | 2001-10-31 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Degenerate interfaces in antigen-antibody complexes. J.Mol.Biol., 313, 2001
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1MPX
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![BU of 1mpx by Molmil](/molmil-images/mine/1mpx) | ALPHA-AMINO ACID ESTER HYDROLASE LABELED WITH SELENOMETHIONINE | Descriptor: | CALCIUM ION, GLYCEROL, alpha-amino acid ester hydrolase | Authors: | Barends, T.R.M, Polderman-Tijmes, J.J, Jekel, P.A, Hensgens, C.M.H, de Vries, E.J, Janssen, D.B, Dijkstra, B.W. | Deposit date: | 2002-09-13 | Release date: | 2003-04-15 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The sequence and crystal structure of the alpha-amino acid ester hydrolase from Xanthomonas citri define a new family of beta-lactam antibiotic acylases. J.Biol.Chem., 278, 2003
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2JYF
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![BU of 2jyf by Molmil](/molmil-images/mine/2jyf) | |
2J9X
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![BU of 2j9x by Molmil](/molmil-images/mine/2j9x) | Tryptophan Synthase in complex with GP, alpha-D,L-glycerol-phosphate, Cs, pH6.5 - alpha aminoacrylate form - (GP)E(A-A) | Descriptor: | 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, CESIUM ION, DIMETHYL SULFOXIDE, ... | Authors: | Ngo, H, Kimmich, N, Harris, R, Niks, D, Blumenstein, L, Kulik, V, Barends, T.R, Schlichting, I, Dunn, M.F. | Deposit date: | 2006-11-16 | Release date: | 2007-06-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Allosteric Regulation of Substrate Channeling in Tryptophan Synthase: Modulation of the L-Serine Reaction in Stage I of the Beta-Reaction by Alpha-Site Ligands. Biochemistry, 46, 2007
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