2J8T
Human aldose reductase in complex with NADP and citrate at 0.82 angstrom
Summary for 2J8T
Entry DOI | 10.2210/pdb2j8t/pdb |
Related | 2FZB 2FZD |
Descriptor | ALDO-KETO REDUCTASE FAMILY 1, MEMBER B1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CITRATE ANION, ... (4 entities in total) |
Functional Keywords | oxidoreductase, nadp, citrate |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 37019.94 |
Authors | Biadene, M.,Hazemann, I.,Cousido, A.,Ginell, S.,Sheldrick, G.M.,Podjarny, A.,Schneider, T.R. (deposition date: 2006-10-27, release date: 2007-05-29, Last modification date: 2023-12-13) |
Primary citation | Biadene, M.,Hazemann, I.,Cousido, A.,Ginell, S.,Joachimiak, A.,Sheldrick, G.M.,Podjarny, A.,Schneider, T.R. The Atomic Resolution Structure of Human Aldose Reductase Reveals that Rearrangement of a Bound Ligand Allows the Opening of the Safety-Belt Loop. Acta Crystallogr.,Sect.D, 63:665-, 2007 Cited by PubMed: 17505104DOI: 10.1107/S0907444907011997 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (0.82 Å) |
Structure validation
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