2J8T
Human aldose reductase in complex with NADP and citrate at 0.82 angstrom
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | ALDO-KETO REDUCTASE FAMILY 1, MEMBER B1 | polymer | 316 | 35898.3 | 1 | UniProt (Q5U031) Pfam (PF00248) UniProt (by SIFTS) (P15121) In PDB | HOMO SAPIENS (HUMAN) | ALDOSE REDUCTASE, CTCL TUMOR ANTIGEN HD-CL-07, ALDOSE REDUCTASE |
2 | A | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
3 | A | CITRATE ANION | non-polymer | 189.1 | 2 | Chemie (FLC) | |||
4 | water | water | 18.0 | 514 | Chemie (HOH) |
Sequence modifications
A: 0 - 315 (UniProt: Q5U031)
PDB | External Database | Details |
---|---|---|
Ile 4 | Leu 5 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 35898.3 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1121.6 | |
All* | Total formula weight | 37019.9 |