2I46

Crystal structure of human TPP1

Summary for 2I46

• Entry DOI: 10.2210/pdb2i46/pdb
• Descriptor: Adrenocortical dysplasia protein homolog (2 entities in total)
• Functional Keywords: tpp1, ob fold, pot1 binding, protein binding
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q96AP0
• Total number of polymer chains: 2
• Total formula weight: 35117.07

Authors

Wang, F.,Podell, E.R.,Zaug, A.J.,Yang, Y.T.,Baciu, P.,Else, T.,Hammer, G.D.,Cech, T.R.,Lei, M. (deposition date: 2006-08-21, release date: 2006-11-28, Last modification date: 2024-02-21)

• Primary citation: Wang, F.,Podell, E.R.,Zaug, A.J.,Yang, Y.,Baciu, P.,Cech, T.R.,Lei, M.; The POT1-TPP1 telomere complex is a telomerase processivity factor.; Nature, 445:506-510, 2007; PubMed: 17237768; DOI: 10.1038/nature05454

Experimental method

X-RAY DIFFRACTION (2.7 Å)