8P31
Structure of human SIT1:ACE2 complex (closed PD conformation) bound to L-pipecolate
Summary for 8P31
Entry DOI | 10.2210/pdb8p31/pdb |
EMDB information | 17382 |
Descriptor | Processed angiotensin-converting enzyme 2, Sodium- and chloride-dependent transporter XTRP3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | amino acid transporter, proline, slc6a20, ace2, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 335111.59 |
Authors | Li, H.Z.,Pike, A.C.W.,Chi, G.,Hansen, J.S.,Lee, S.G.,Rodstrom, K.E.J.,Bushell, S.R.,Speedman, D.,Evans, A.,Wang, D.,He, D.,Shrestha, L.,Nasrallah, C.,Chalk, R.,Moreira, T.,MacLean, E.M.,Marsden, B.,Bountra, C.,Burgess-Brown, N.A.,Dafforn, T.R.,Carpenter, E.P.,Sauer, D.B. (deposition date: 2023-05-16, release date: 2024-06-12) |
Primary citation | Li, H.Z.,Pike, A.C.W.,Chi, G.,Hansen, J.S.,Lee, S.G.,Rodstrom, K.E.J.,Bushell, S.R.,Speedman, D.,Evans, A.,Wang, D.,He, D.,Shrestha, L.,Nasrallah, C.,Burgess-Brown, N.A.,Dafforn, T.R.,Carpenter, E.P.,Sauer, D.B. Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2 To Be Published, |
Experimental method | ELECTRON MICROSCOPY (3.24 Å) |
Structure validation
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