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PDB: 17 results

2M8T
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BU of 2m8t by Molmil
Solution NMR structure of the V209M variant of the human prion protein (residues 90-231)
Descriptor: Major prion protein
Authors:Mills, J.L, Surewicz, K, Surewicz, W, Soennichsen, F.D.
Deposit date:2013-05-28
Release date:2013-09-11
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Thermodynamic Stabilization of the Folded Domain of Prion Protein Inhibits Prion Infection in Vivo.
Cell Rep, 4, 2013
2K1D
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NMR Studies of a Pathogenic Mutant (D178N) of the Human Prion Protein
Descriptor: Major prion protein
Authors:Mills, J.L, Surewicz, K, Surewicz, W.K, Sonnichsen, F.D.
Deposit date:2008-02-29
Release date:2009-03-03
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Residue 129 polymorphism and conformational dynamics of familial prion diseases associated with the human prion protein variant D178N
To be Published
3HEQ
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Human prion protein variant D178N with M129
Descriptor: CADMIUM ION, Major prion protein
Authors:Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
Deposit date:2009-05-10
Release date:2010-01-12
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HES
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Human prion protein variant F198S with M129
Descriptor: CADMIUM ION, Major prion protein
Authors:Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
Deposit date:2009-05-10
Release date:2010-01-12
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HAF
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BU of 3haf by Molmil
Human prion protein variant V129 domain swapped dimer
Descriptor: CADMIUM ION, CHLORIDE ION, Major prion protein
Authors:Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
Deposit date:2009-05-01
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HAK
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BU of 3hak by Molmil
Human prion protein variant V129
Descriptor: Major prion protein
Authors:Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
Deposit date:2009-05-01
Release date:2010-01-12
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HER
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BU of 3her by Molmil
Human prion protein variant F198S with V129
Descriptor: CADMIUM ION, Major prion protein
Authors:Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
Deposit date:2009-05-10
Release date:2010-01-12
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HJX
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BU of 3hjx by Molmil
Human prion protein variant D178N with V129
Descriptor: CADMIUM ION, CHLORIDE ION, Major prion protein
Authors:Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
Deposit date:2009-05-22
Release date:2010-01-12
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HJ5
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Human prion protein variant V129 domain swapped dimer
Descriptor: Major prion protein
Authors:Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
Deposit date:2009-05-20
Release date:2010-01-12
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
8DJA
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BU of 8dja by Molmil
Cryo-EM structure of mouse PrP23-144 amyloid fibrils (polymorph 1)
Descriptor: Major prion protein
Authors:Li, Q, Surewicz, W.K.
Deposit date:2022-06-30
Release date:2022-09-07
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.92 Å)
Cite:Cryo-EM structure of disease-related prion fibrils provides insights into seeding barriers.
Nat.Struct.Mol.Biol., 29, 2022
1I4M
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Crystal structure of the human prion protein reveals a mechanism for oligomerization
Descriptor: CADMIUM ION, CHLORIDE ION, MAJOR PRION PROTEIN
Authors:Knaus, K.J, Morillas, M, Swietnicki, W, Malone, M, Surewicz, W.K, Yee, V.C.
Deposit date:2001-02-22
Release date:2002-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the human prion protein reveals a mechanism for oligomerization.
Nat.Struct.Biol., 8, 2001
7KWZ
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BU of 7kwz by Molmil
TDP-43 LCD amyloid fibrils
Descriptor: Isoform 2 of TAR DNA-binding protein 43
Authors:Li, Q, Babinchak, W.M, Surewicz, W.K.
Deposit date:2020-12-02
Release date:2021-02-24
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of amyloid fibrils formed by the entire low complexity domain of TDP-43.
Nat Commun, 12, 2021
7RL4
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BU of 7rl4 by Molmil
Cryo-EM structure of human PrP23-144 amyloid fibrils
Descriptor: Major prion protein
Authors:Li, Q, Surewicz, W.K.
Deposit date:2021-07-23
Release date:2022-07-27
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Cryo-EM structure of disease-related prion fibrils provides insights into seeding barriers.
Nat.Struct.Mol.Biol., 29, 2022
1FKC
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BU of 1fkc by Molmil
HUMAN PRION PROTEIN (MUTANT E200K) FRAGMENT 90-231
Descriptor: PRION PROTEIN
Authors:Zhang, Y, Swietnicki, W, Zagorski, M.G, Surewicz, W.K, Soennichsen, F.D.
Deposit date:2000-08-09
Release date:2000-09-21
Last modified:2018-03-14
Method:SOLUTION NMR
Cite:Solution structure of the E200K variant of human prion protein. Implications for the mechanism of pathogenesis in familial prion diseases.
J.Biol.Chem., 275, 2000
1FO7
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BU of 1fo7 by Molmil
HUMAN PRION PROTEIN MUTANT E200K FRAGMENT 90-231
Descriptor: PRION PROTEIN
Authors:Zhang, Y, Swietnicki, W, Zagorski, M.G, Surewicz, W.K, Soennichsen, F.D.
Deposit date:2000-08-25
Release date:2000-09-21
Last modified:2024-10-09
Method:SOLUTION NMR
Cite:Solution structure of the E200K variant of human prion protein. Implications for the mechanism of pathogenesis in familial prion diseases.
J.Biol.Chem., 275, 2000
4E1H
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BU of 4e1h by Molmil
Fragment of human prion protein
Descriptor: CITRIC ACID, FE (III) ION, Major prion protein
Authors:Apostol, M.I, Perry, K, Surewicz, W.K.
Deposit date:2012-03-06
Release date:2013-03-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of a human prion protein fragment reveals a motif for oligomer formation.
J.Am.Chem.Soc., 135, 2013
4E1I
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BU of 4e1i by Molmil
Fragment of human prion protein
Descriptor: Major prion protein
Authors:Apostol, M.I, Surewicz, W.K.
Deposit date:2012-03-06
Release date:2013-03-06
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Crystal structure of a human prion protein fragment reveals a motif for oligomer formation.
J.Am.Chem.Soc., 135, 2013

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