4E1I
Fragment of human prion protein
Summary for 4E1I
Entry DOI | 10.2210/pdb4e1i/pdb |
Related | 4E1H |
Descriptor | Major prion protein (3 entities in total) |
Functional Keywords | beta prism, amyloid-related oligomer, protein fibril, cell cycle |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Lipid-anchor, GPI-anchor. Isoform 2: Cytoplasm: P04156 P04156 |
Total number of polymer chains | 12 |
Total formula weight | 8547.85 |
Authors | Apostol, M.I.,Surewicz, W.K. (deposition date: 2012-03-06, release date: 2013-03-06, Last modification date: 2013-11-27) |
Primary citation | Apostol, M.I.,Perry, K.,Surewicz, W.K. Crystal structure of a human prion protein fragment reveals a motif for oligomer formation. J.Am.Chem.Soc., 135:10202-10205, 2013 Cited by PubMed: 23808589DOI: 10.1021/ja403001q PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.03 Å) |
Structure validation
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