3HJX

Human prion protein variant D178N with V129

Summary for 3HJX

Entry DOI	10.2210/pdb3hjx/pdb
Related	3HAF 3HAK 3HEQ 3HER 3HES 3HJ5
Descriptor	Major prion protein, CADMIUM ION, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	prion protein, cell membrane, disease mutation, disulfide bond, glycoprotein, golgi apparatus, gpi-anchor, lipoprotein, membrane, polymorphism, prion, membrane protein
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Lipid-anchor, GPI-anchor . Isoform 2: Cytoplasm : P04156
Total number of polymer chains	1
Total formula weight	12792.83
Authors	Lee, S.,Antony, L.,Hartmann, R.,Knaus, K.J.,Surewicz, K.,Surewicz, W.K.,Yee, V.C. (deposition date: 2009-05-22, release date: 2010-01-12, Last modification date: 2021-10-13)
Primary citation	Lee, S.,Antony, L.,Hartmann, R.,Knaus, K.J.,Surewicz, K.,Surewicz, W.K.,Yee, V.C. Conformational diversity in prion protein variants influences intermolecular beta-sheet formation. Embo J., 29:251-262, 2010 Cited by PubMed: 19927125 DOI: 10.1038/emboj.2009.333 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation