3HJX

Human prion protein variant D178N with V129

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016020	cellular_component	membrane
A	0051260	biological_process	protein homooligomerization

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CD A 300

Chain	Residue
A	HIS140
A	ASP147
A	HIS177
A	HOH302
A	HOH350
A	HOH354

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 301

Chain	Residue
A	ASN173

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Functional Information from PROSITE/UniProt

site_id	PS00706
Number of Residues	19
Details	PRION_2 Prion protein signature 2. EtDvKMMeRVVeQMCitQY

Chain	Residue	Details
A	GLU200-TYR218

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	LIPID: GPI-anchor amidated serine => ECO:0000250|UniProtKB:P04273

Chain	Residue	Details
A	SER230

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site_id	SWS_FT_FI2
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:12214108

Chain	Residue	Details
A	ASN181

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site_id	SWS_FT_FI3
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19349973

Chain	Residue	Details
A	ASN197

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