7RL4

Cryo-EM structure of human PrP23-144 amyloid fibrils

Summary for 7RL4

Entry DOI	10.2210/pdb7rl4/pdb
EMDB information	24514
Descriptor	Major prion protein (1 entity in total)
Functional Keywords	prion, amyloid, protein fibril
Biological source	Homo sapiens (Human)
Total number of polymer chains	20
Total formula weight	250834.86
Authors	Li, Q.,Surewicz, W.K. (deposition date: 2021-07-23, release date: 2022-07-27, Last modification date: 2024-06-05)
Primary citation	Li, Q.,Jaroniec, C.P.,Surewicz, W.K. Cryo-EM structure of disease-related prion fibrils provides insights into seeding barriers. Nat.Struct.Mol.Biol., 29:962-965, 2022 Cited by PubMed: 36097290 DOI: 10.1038/s41594-022-00833-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.86 Å)

Structure validation