7RL4

Cryo-EM structure of human PrP23-144 amyloid fibrils

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, K, P, C...)	Major prion protein	polymer	126	12541.7	20	UniProt (P04156)	Homo sapiens (Human)	PrP,ASCR,PrP27-30,PrP33-35C

Sequence modifications

A, B, K, P, C, G, L, Q, D, H, M, R, E, I, N, S, F, J, O, T: 23 - 144 (UniProt: P04156)

PDB	External Database	Details
Gly 19	-	expression tag
Ser 20	-	expression tag
Asp 21	-	expression tag
Pro 22	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	20
	Total formula weight	250834.9
All*	Total formula weight	250834.9

*Water molecules are not included.