1FKC
HUMAN PRION PROTEIN (MUTANT E200K) FRAGMENT 90-231
Summary for 1FKC
| Entry DOI | 10.2210/pdb1fkc/pdb |
| Descriptor | PRION PROTEIN (1 entity in total) |
| Functional Keywords | three helix, creutzfeldt-jakob disease, prion, aggregation, membrane protein |
| Biological source | Homo sapiens (human) |
| Cellular location | Cell membrane; Lipid-anchor, GPI-anchor . Isoform 2: Cytoplasm : P04156 |
| Total number of polymer chains | 1 |
| Total formula weight | 16169.06 |
| Authors | Zhang, Y.,Swietnicki, W.,Zagorski, M.G.,Surewicz, W.K.,Soennichsen, F.D. (deposition date: 2000-08-09, release date: 2000-09-21, Last modification date: 2018-03-14) |
| Primary citation | Zhang, Y.,Swietnicki, W.,Zagorski, M.G.,Surewicz, W.K.,Sonnichsen, F.D. Solution structure of the E200K variant of human prion protein. Implications for the mechanism of pathogenesis in familial prion diseases. J.Biol.Chem., 275:33650-33654, 2000 Cited by PubMed: 10954699DOI: 10.1074/jbc.C000483200 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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