7KWZ

TDP-43 LCD amyloid fibrils

Summary for 7KWZ

Entry DOI	10.2210/pdb7kwz/pdb
EMDB information	23059
Descriptor	Isoform 2 of TAR DNA-binding protein 43 (1 entity in total)
Functional Keywords	tdp-43, amyloid, neurodegenerative diseases, amyotropic lateral sclerosis, protein fibril
Biological source	Homo sapiens (Human)
Total number of polymer chains	5
Total formula weight	72852.41
Authors	Li, Q.,Babinchak, W.M.,Surewicz, W.K. (deposition date: 2020-12-02, release date: 2021-02-24, Last modification date: 2024-03-06)
Primary citation	Li, Q.,Babinchak, W.M.,Surewicz, W.K. Cryo-EM structure of amyloid fibrils formed by the entire low complexity domain of TDP-43. Nat Commun, 12:1620-1620, 2021 Cited by PubMed: 33712624 DOI: 10.1038/s41467-021-21912-y PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation