3HAK
Human prion protein variant V129
Summary for 3HAK
Entry DOI | 10.2210/pdb3hak/pdb |
Related | 3HAF 3HEQ 3HER 3HES |
Descriptor | Major prion protein (2 entities in total) |
Functional Keywords | prion protein, cell membrane, disease mutation, disulfide bond, glycoprotein, golgi apparatus, gpi-anchor, lipoprotein, membrane, polymorphism, prion, membrane protein |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Lipid-anchor, GPI-anchor . Isoform 2: Cytoplasm : P04156 |
Total number of polymer chains | 1 |
Total formula weight | 12370.71 |
Authors | Lee, S.,Antony, L.,Hartmann, R.,Knaus, K.J.,Surewicz, K.,Surewicz, W.K.,Yee, V.C. (deposition date: 2009-05-01, release date: 2010-01-12, Last modification date: 2017-11-01) |
Primary citation | Lee, S.,Antony, L.,Hartmann, R.,Knaus, K.J.,Surewicz, K.,Surewicz, W.K.,Yee, V.C. Conformational diversity in prion protein variants influences intermolecular beta-sheet formation. Embo J., 29:251-262, 2010 Cited by PubMed: 19927125DOI: 10.1038/emboj.2009.333 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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