2M8T
Solution NMR structure of the V209M variant of the human prion protein (residues 90-231)
Summary for 2M8T
| Entry DOI | 10.2210/pdb2m8t/pdb |
| NMR Information | BMRB: 19268 |
| Descriptor | Major prion protein (1 entity in total) |
| Functional Keywords | membrane protein, cell cycle |
| Biological source | Homo sapiens (human) |
| Cellular location | Cell membrane; Lipid-anchor, GPI-anchor. Isoform 2: Cytoplasm: P04156 |
| Total number of polymer chains | 1 |
| Total formula weight | 16557.40 |
| Authors | Mills, J.L.,Surewicz, K.,Surewicz, W.,Soennichsen, F.D. (deposition date: 2013-05-28, release date: 2013-09-11, Last modification date: 2023-06-14) |
| Primary citation | Kong, Q.,Mills, J.L.,Kundu, B.,Li, X.,Qing, L.,Surewicz, K.,Cali, I.,Huang, S.,Zheng, M.,Swietnicki, W.,Sonnichsen, F.D.,Gambetti, P.,Surewicz, W.K. Thermodynamic Stabilization of the Folded Domain of Prion Protein Inhibits Prion Infection in Vivo. Cell Rep, 4:248-254, 2013 Cited by PubMed: 23871665DOI: 10.1016/j.celrep.2013.06.030 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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