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PDB: 182 件

3KF6
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Crystal structure of S. pombe Stn1-ten1 complex
分子名称: Protein stn1, Protein ten1
著者Sun, J, Yu, E.Y, Yang, Y.T, Confer, L.A, Sun, S.H, Wan, K, Lue, N.F, Lei, M.
登録日2009-10-27
公開日2009-12-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Stn1-Ten1 is an Rpa2-Rpa3-like complex at telomeres.
Genes Dev., 23, 2009
3KEY
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Crystal structure of S. cerevisiae Stn1 C-terminal
分子名称: Protein STN1
著者Sun, J, Yu, E.Y, Yang, Y.T, Confer, L.A, Sun, S.H, Wan, K, Lue, N.F, Lei, M.
登録日2009-10-26
公開日2009-12-22
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Stn1-Ten1 is an Rpa2-Rpa3-like complex at telomeres.
Genes Dev., 23, 2009
3KF8
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Crystal structure of C. tropicalis Stn1-ten1 complex
分子名称: Protein stn1, Protein ten1
著者Sun, J, Yu, E.Y, Yang, Y.T, Confer, L.A, Sun, S.H, Wan, K, Lue, N.F, Lei, M.
登録日2009-10-27
公開日2009-12-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Stn1-Ten1 is an Rpa2-Rpa3-like complex at telomeres.
Genes Dev., 23, 2009
8SMC
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Cryo-EM structure of LRRK2 bound with type-I inhibitor DNL201
分子名称: 2-methyl-2-(3-methyl-4-{[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1H-pyrazol-1-yl)propanenitrile, GUANOSINE-5'-DIPHOSPHATE, non-specific serine/threonine protein kinase
著者Sun, J, Zhu, H.
登録日2023-04-26
公開日2024-01-03
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Rab29-dependent asymmetrical activation of leucine-rich repeat kinase 2.
Science, 382, 2023
8JEL
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Crystal structure of TIGIT in complexed with Ociperlimab, crystal form I
分子名称: T-cell immunoreceptor with Ig and ITIM domains, antibody heavy chain, antibody light chain
著者Sun, J, Zhang, X.X, Song, J.
登録日2023-05-16
公開日2024-02-28
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab.
Structure, 32, 2024
8JEQ
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Crystal structure of Tiragolumab
分子名称: antibody heavy chain, antibody light chain
著者Sun, J, Zhang, X.X, Song, J.
登録日2023-05-16
公開日2024-02-28
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab.
Structure, 32, 2024
8JEP
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Crystal structure of Ociperlimab
分子名称: antibody heavy chain, antibody light chain
著者Sun, J, Zhang, X.X, Song, J.
登録日2023-05-16
公開日2024-02-28
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab.
Structure, 32, 2024
8JEO
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Crystal structure of TIGIT in complexed with Tiragolumab
分子名称: T-cell immunoreceptor with Ig and ITIM domains, antibody heavy chain, antibody light chain
著者Sun, J, Zhang, X.X, Song, J.
登録日2023-05-16
公開日2024-02-28
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab.
Structure, 32, 2024
8JEN
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Crystal structure of TIGIT in complexed with Ociperlimab, crystal form II
分子名称: T-cell immunoreceptor with Ig and ITIM domains, antibody heavy chain, antibody light chain
著者Sun, J, Zhang, X.X, Song, J.
登録日2023-05-16
公開日2024-02-28
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab.
Structure, 32, 2024
8RFZ
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Structure of E166A BlaC from Mycobacterium tuberculosis at pH 4.5
分子名称: Beta-lactamase, SULFATE ION
著者Sun, J, Bruenle, S, Ubbink, M.
登録日2023-12-13
公開日2024-08-28
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献A low-barrier proton shared between two aspartates acts as a conformational switch that changes the substrate specificity of the beta-lactamase BlaC.
Int.J.Biol.Macromol., 278, 2024
8RII
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Structure of E166A BlaC from Mycobacterium tuberculosis at pH 6.5
分子名称: Beta-lactamase
著者Sun, J, Bruenle, S, Ubbink, M.
登録日2023-12-18
公開日2024-08-28
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A low-barrier proton shared between two aspartates acts as a conformational switch that changes the substrate specificity of the beta-lactamase BlaC.
Int.J.Biol.Macromol., 278, 2024
8RG2
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Structure of BlaC from Mycobacterium tuberculosis at pH 8
分子名称: Beta-lactamase, GLYCEROL
著者Sun, J, Bruenle, S, Ubbink, M.
登録日2023-12-13
公開日2024-08-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A low-barrier proton shared between two aspartates acts as a conformational switch that changes the substrate specificity of the beta-lactamase BlaC.
Int.J.Biol.Macromol., 278, 2024
1YOP
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BU of 1yop by Molmil
The solution structure of Kti11p
分子名称: Kti11p, ZINC ION
著者Sun, J, Zhang, J, Wu, F, Xu, C, Li, S, Zhao, W, Wu, Z, Wu, J, Zhou, C.-Z, Shi, Y.
登録日2005-01-28
公開日2005-04-05
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of Kti11p from Saccharomyces cerevisiae reveals a novel zinc-binding module.
Biochemistry, 44, 2005
6WXV
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CryoEM structure of mouse DUOX1-DUOXA1 complex in the presence of NADPH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Sun, J.
登録日2020-05-12
公開日2020-09-02
最終更新日2021-03-17
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structures of mouse DUOX1-DUOXA1 provide mechanistic insights into enzyme activation and regulation.
Nat.Struct.Mol.Biol., 27, 2020
6WXU
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CryoEM structure of mouse DUOX1-DUOXA1 complex in the dimer-of-dimer state
分子名称: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Sun, J.
登録日2020-05-12
公開日2020-09-02
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structures of mouse DUOX1-DUOXA1 provide mechanistic insights into enzyme activation and regulation.
Nat.Struct.Mol.Biol., 27, 2020
5DUM
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BU of 5dum by Molmil
Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody 65C6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 65C6 Heavy Chain, 65C6 Light Chain, ...
著者Sun, J, Zuo, T, Wang, G, Zhou, P, Zhang, L, Wang, X.
登録日2015-09-19
公開日2015-12-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.003 Å)
主引用文献Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection
Nat Commun, 6, 2015
8OE1
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Structure of P167S BlaC from Mycobacterium tuberculosis at pH 5
分子名称: Beta-lactamase, GLYCEROL
著者Sun, J, Chikunova, A, Ubbink, M.
登録日2023-03-10
公開日2023-08-23
最終更新日2024-10-02
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Enhanced activity against a third-generation cephalosporin by destabilization of the active site of a class A beta-lactamase.
Int.J.Biol.Macromol., 250, 2023
8EYT
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BU of 8eyt by Molmil
30S_delta_ksgA+KsgA complex
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Sun, J, Kinman, L.F, Jahagirdar, D, Ortega, J, Davis, J.H.
登録日2022-10-28
公開日2023-09-06
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献KsgA facilitates ribosomal small subunit maturation by proofreading a key structural lesion.
Nat.Struct.Mol.Biol., 30, 2023
8JBJ
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Crystal structure of anti-PVRIG Fab
分子名称: antibody heavy chain, antibody light chain
著者Sun, J, Li, X.L, Song, J.
登録日2023-05-09
公開日2023-06-21
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Identification and characterization of an unexpected isomerization motif in CDRH2 that affects antibody activity.
Mabs, 15, 2023
6WXR
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CryoEM structure of mouse DUOX1-DUOXA1 complex in the absence of NADPH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Dual oxidase 1, Dual oxidase maturation factor 1, ...
著者Sun, J.
登録日2020-05-11
公開日2020-09-02
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structures of mouse DUOX1-DUOXA1 provide mechanistic insights into enzyme activation and regulation.
Nat.Struct.Mol.Biol., 27, 2020
8OE5
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Structure of P167S BlaC from Mycobacterium tuberculosis at pH 6.3
分子名称: Beta-lactamase, CITRATE ANION, GLYCEROL
著者Sun, J, Chikunova, A, Ubbink, M.
登録日2023-03-10
公開日2023-08-23
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Enhanced activity against a third-generation cephalosporin by destabilization of the active site of a class A beta-lactamase.
Int.J.Biol.Macromol., 250, 2023
6CW2
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Crystal structure of a yeast SAGA transcriptional coactivator Ada2/Gcn5 HAT subcomplex, crystal form 1
分子名称: Histone acetyltransferase GCN5, Transcriptional adapter 2, ZINC ION, ...
著者Sun, J, Paduch, M, Kim, S.A, Kramer, R.M, Barrios, A.F, Lu, V, Luke, J, Usatyuk, S, Kossiakoff, A.A, Tan, S.
登録日2018-03-29
公開日2018-09-19
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CW3
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Crystal structure of a yeast SAGA transcriptional coactivator Ada2/Gcn5 HAT subcomplex, crystal form 2
分子名称: Histone acetyltransferase GCN5, Transcriptional adapter 2, ZINC ION, ...
著者Sun, J, Paduch, M, Kim, S.A, Kramer, R.M, Barrios, A.F, Lu, V, Luke, J, Usatyuk, S, Kossiakoff, A.A, Tan, S.
登録日2018-03-29
公開日2018-09-19
最終更新日2020-03-04
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3OIP
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Crystal structure of Yeast telomere protein Cdc13 OB1
分子名称: Cell division control protein 13
著者Sun, J, Yang, Y, Wan, K, Mao, N, Yu, T.Y, Lin, Y.C, DeZwaan, D.C, Freeman, B.C, Lin, J.J, Lue, N.F, Lei, M.
登録日2010-08-19
公開日2010-11-03
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.504 Å)
主引用文献Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase alpha.
Cell Res., 21, 2011
3RMH
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Crystal Structure of yeast telomere protein Cdc13 OB4
分子名称: Yeast Cdc13 OB4
著者Sun, J, Yang, Y, Lei, M.
登録日2011-04-20
公開日2011-11-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献Analyses of Candida Cdc13 Orthologues Revealed a Novel OB Fold Dimer Arrangement, Dimerization-Assisted DNA Binding, and Substantial Structural Differences between Cdc13 and RPA70.
Mol.Cell.Biol., 32, 2012

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