6CW3

Crystal structure of a yeast SAGA transcriptional coactivator Ada2/Gcn5 HAT subcomplex, crystal form 2

Summary for 6CW3

Entry DOI	10.2210/pdb6cw3/pdb
Descriptor	antibody heavy chain, antibody light chain, Histone acetyltransferase GCN5, ... (6 entities in total)
Functional Keywords	ada2/gcn5 structure, gene regulation
Biological source	Homo sapiens (Human) More
Total number of polymer chains	8
Total formula weight	183548.77
Authors	Sun, J.,Paduch, M.,Kim, S.A.,Kramer, R.M.,Barrios, A.F.,Lu, V.,Luke, J.,Usatyuk, S.,Kossiakoff, A.A.,Tan, S. (deposition date: 2018-03-29, release date: 2018-09-19, Last modification date: 2020-03-04)
Primary citation	Sun, J.,Paduch, M.,Kim, S.A.,Kramer, R.M.,Barrios, A.F.,Lu, V.,Luke, J.,Usatyuk, S.,Kossiakoff, A.A.,Tan, S. Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2. Proc. Natl. Acad. Sci. U.S.A., 115:10010-10015, 2018 Cited by PubMed: 30224453 DOI: 10.1073/pnas.1805343115 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.98 Å)

Structure validation