6CW3

Crystal structure of a yeast SAGA transcriptional coactivator Ada2/Gcn5 HAT subcomplex, crystal form 2

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0008270	molecular_function	zinc ion binding
F	0004402	molecular_function	histone acetyltransferase activity
F	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
G	0008270	molecular_function	zinc ion binding
H	0004402	molecular_function	histone acetyltransferase activity
H	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN E 201

Chain	Residue
E	CYS7
E	CYS10
E	CYS31
E	CYS34

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site_id	AC2
Number of Residues	4
Details	binding site for residue ZN E 202

Chain	Residue
E	CYS22
E	CYS25
E	HIS44
E	HIS48

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN G 201

Chain	Residue
G	CYS10
G	CYS31
G	CYS34
G	CYS7

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN G 202

Chain	Residue
G	CYS22
G	CYS25
G	HIS44
G	HIS48

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
A	TYR207-HIS213
B	TYR193-HIS199

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site_id	PS01357
Number of Residues	28
Details	ZF_ZZ_1 Zinc finger ZZ-type signature. CdvCsadctnrvRVsCai...CpEYdLCvpC

Chain	Residue	Details
E	CYS7-CYS34

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	112
Details	ZN_FING: ZZ-type => ECO:0000255|PROSITE-ProRule:PRU00228

Chain	Residue	Details
E	SER2-TYR58
G	SER2-TYR58

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00228

Chain	Residue	Details
E	CYS7
G	CYS10
G	CYS22
G	CYS25
G	CYS31
G	CYS34
G	HIS44
G	HIS48
E	CYS10
E	CYS22
E	CYS25
E	CYS31
E	CYS34
E	HIS44
E	HIS48
G	CYS7

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	SITE: Important for catalytic activity

Chain	Residue	Details
F	GLU173
H	GLU173

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