6WXV

CryoEM structure of mouse DUOX1-DUOXA1 complex in the presence of NADPH

Summary for 6WXV

• Entry DOI: 10.2210/pdb6wxv/pdb
• EMDB information: 21964
• Descriptor: Dual oxidase 1, Dual oxidase maturation factor 1, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• Functional Keywords: membrane protein, protein complex, nadph oxidase, ros production
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 2
• Total formula weight: 218586.09

Authors

Sun, J. (deposition date: 2020-05-12, release date: 2020-09-02, Last modification date: 2021-03-17)

• Primary citation: Sun, J.; Structures of mouse DUOX1-DUOXA1 provide mechanistic insights into enzyme activation and regulation.; Nat.Struct.Mol.Biol., 27:1086-1093, 2020; PubMed: 32929281; DOI: 10.1038/s41594-020-0501-x

Experimental method

ELECTRON MICROSCOPY (3.3 Å)