6WXV
CryoEM structure of mouse DUOX1-DUOXA1 complex in the presence of NADPH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dual oxidase 1 | polymer | 1536 | 175739.8 | 1 | UniProt (A2AQ92) Pfam (PF03098) Pfam (PF00036) Pfam (PF13499) Pfam (PF01794) Pfam (PF08022) Pfam (PF08030) | Mus musculus (Mouse) | |
| 2 | B (B) | Dual oxidase maturation factor 1 | polymer | 341 | 37619.7 | 1 | UniProt (Q8VE49) Pfam (PF10204) | Mus musculus (Mouse) | Dual oxidase activator 1 |
| 3 | C (C) | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G10756ZZ) | |||
| 4 | D (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) | |||
| 5 | E, F, G, M (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 6 | H, I (A) | HEME B/C | non-polymer | 618.5 | 2 | Chemie (HEB) | |||
| 7 | J (A) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 8 | K (A) | DIUNDECYL PHOSPHATIDYL CHOLINE | non-polymer | 622.8 | 1 | Chemie (PLC) | |||
| 9 | L (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) |
Sequence modifications
A: 20 - 1551 (UniProt: A2AQ92)
| PDB | External Database | Details |
|---|---|---|
| Gly 16 | - | expression tag |
| Pro 17 | - | expression tag |
| Ser 18 | - | expression tag |
| Arg 19 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 213359.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 910.8 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 4315.7 | |
| All* | Total formula weight | 218586.1 |
