8OE5

Structure of P167S BlaC from Mycobacterium tuberculosis at pH 6.3

Summary for 8OE5

Entry DOI	10.2210/pdb8oe5/pdb
Descriptor	Beta-lactamase, GLYCEROL, CITRATE ANION, ... (4 entities in total)
Functional Keywords	hydrolase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	2
Total formula weight	57087.76
Authors	Sun, J.,Chikunova, A.,Ubbink, M. (deposition date: 2023-03-10, release date: 2023-08-23, Last modification date: 2024-01-24)
Primary citation	Sun, J.,Chikunova, A.,Boyle, A.L.,Voskamp, P.,Timmer, M.,Ubbink, M. Enhanced activity against a third-generation cephalosporin by destabilization of the active site of a class A beta-lactamase. Int.J.Biol.Macromol., 250:126160-126160, 2023 Cited by PubMed: 37549761 DOI: 10.1016/j.ijbiomac.2023.126160 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation