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PDB: 278 results

1KC8
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Co-crystal Structure of Blasticidin S Bound to the 50S Ribosomal Subunit
Descriptor: 23S RRNA, 5S RRNA, BLASTICIDIN S, ...
Authors:Hansen, J.L, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A.
Deposit date:2001-11-07
Release date:2003-07-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit
J.Mol.Biol., 330, 2003
1K73
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BU of 1k73 by Molmil
Co-crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit
Descriptor: 23S RRNA, 5S RRNA, ANISOMYCIN, ...
Authors:Hansen, J, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A.
Deposit date:2001-10-18
Release date:2003-07-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit
J.Mol.Biol., 330, 2003
4YLP
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BU of 4ylp by Molmil
E. coli Transcription Initiation Complex - 16-bp spacer and 5-nt RNA
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuo, Y, Steitz, T.A.
Deposit date:2015-03-05
Release date:2015-04-22
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble.
Mol.Cell, 58, 2015
4YLO
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E. coli Transcription Initiation Complex - 16-bp spacer and 4-nt RNA
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuo, Y, Steitz, T.A.
Deposit date:2015-03-05
Release date:2015-04-22
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (6 Å)
Cite:Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble.
Mol.Cell, 58, 2015
4YLN
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E. coli Transcription Initiation Complex - 17-bp spacer and 4-nt RNA
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Zuo, Y, Steitz, T.A.
Deposit date:2015-03-05
Release date:2015-04-22
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble.
Mol.Cell, 58, 2015
4KJZ
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BU of 4kjz by Molmil
Crystal Structure of Thermus Thermophilus IF2, Apo and GDP-bound Forms (2-474)
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Translation initiation factor IF-2
Authors:Eiler, D.R, Lin, J, Steitz, T.A.
Deposit date:2013-05-04
Release date:2013-09-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Initiation factor 2 crystal structure reveals a different domain organization from eukaryotic initiation factor 5B and mechanism among translational GTPases.
Proc.Natl.Acad.Sci.USA, 110, 2013
4Z8C
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BU of 4z8c by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome bound to translation inhibitor oncocin
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Roy, R.N, Lomakin, I.B, Gagnon, M.G, Steitz, T.A.
Deposit date:2015-04-08
Release date:2015-05-20
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin.
Nat.Struct.Mol.Biol., 22, 2015
4Y4O
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BU of 4y4o by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome with rRNA modifications and bound to protein Y (YfiA) at 2.3A resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
Authors:Polikanov, Y.S, Melnikov, S.V, Soll, D, Steitz, T.A.
Deposit date:2015-02-10
Release date:2015-03-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly.
Nat.Struct.Mol.Biol., 22, 2015
4Y4P
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BU of 4y4p by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome with rRNA modifications and bound to mRNA and A-, P- and E-site tRNAs at 2.5A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Polikanov, Y.S, Melnikov, S.V, Soll, D, Steitz, T.A.
Deposit date:2015-02-10
Release date:2015-03-18
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly.
Nat.Struct.Mol.Biol., 22, 2015
4KZX
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BU of 4kzx by Molmil
Rabbit 40S ribosomal subunit in complex with eIF1.
Descriptor: 18S ribosomal RNA, 40S Ribosomal protein S9, 40S ribosomal protein RACK1, ...
Authors:Lomakin, I.B, Steitz, T.A.
Deposit date:2013-05-30
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (7.809 Å)
Cite:The initiation of mammalian protein synthesis and mRNA scanning mechanism.
Nature, 500, 2013
4KZY
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BU of 4kzy by Molmil
Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A.
Descriptor: 18S Ribosomal RNA, 40S Ribosomal Protein RACK1, 40S Ribosomal Protein S10, ...
Authors:Lomakin, I.B, Steitz, T.A.
Deposit date:2013-05-30
Release date:2013-07-24
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (7.01 Å)
Cite:The initiation of mammalian protein synthesis and mRNA scanning mechanism.
Nature, 500, 2013
4KZZ
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BU of 4kzz by Molmil
Rabbit 40S ribosomal subunit in complex with mRNA, initiator tRNA and eIF1A
Descriptor: 18S Ribosomal RNA, 40S Ribosomal Protein RACK1, 40S Ribosomal Protein S10, ...
Authors:Lomakin, I.B, Steitz, T.A.
Deposit date:2013-05-30
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (7.0305 Å)
Cite:The initiation of mammalian protein synthesis and mRNA scanning mechanism.
Nature, 500, 2013
4JKR
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BU of 4jkr by Molmil
Crystal Structure of E. coli RNA Polymerase in complex with ppGpp
Descriptor: DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA', DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Zuo, Y, Wang, Y, Steitz, T.A.
Deposit date:2013-03-11
Release date:2013-05-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:The mechanism of E. coli RNA polymerase regulation by ppGpp is suggested by the structure of their complex.
Mol.Cell, 50, 2013
4Z3S
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BU of 4z3s by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with antibiotic A201A, mRNA and three tRNAs in the A, P and E sites at 2.65A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 3'-deoxy-3'-{[(2E)-3-(4-{[(4Z)-6-O-(6-deoxy-3,4-di-O-methyl-alpha-D-mannopyranosyl)-5-O-methyl-alpha-D-threo-hex-4-enofuranosyl]oxy}phenyl)-2-methylprop-2-enoyl]amino}-N,N-dimethyladenosine, ...
Authors:Polikanov, Y.S, Starosta, A.L, Juette, M.F, Altman, R.B, Terry, D.S, Lu, W, Burnett, B.J, Dinos, G, Reynolds, K, Blanchard, S.C, Steitz, T.A, Wilson, D.N.
Deposit date:2015-03-31
Release date:2015-06-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.
Mol.Cell, 58, 2015
4M6F
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BU of 4m6f by Molmil
Dimer of the G-Segment Invertase bound to a DNA substrate
Descriptor: DNA-invertase, gix site analog
Authors:Ritacco, C.J, Wang, J, Steitz, T.A.
Deposit date:2013-08-09
Release date:2014-03-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.99 Å)
Cite:Exploiting large non-isomorphous differences for phase determination of a G-segment invertase-DNA complex.
Acta Crystallogr.,Sect.D, 70, 2014
4M4W
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BU of 4m4w by Molmil
Mechanistic implications for the bacterial primosome assembly of the structure of a helicase-helicase loader complex
Descriptor: DNA primase, Primosomal protein DnaI, Replicative helicase
Authors:Liu, B, Eliason, W.K, Steitz, T.A.
Deposit date:2013-08-07
Release date:2013-09-25
Last modified:2013-10-02
Method:X-RAY DIFFRACTION (6.1 Å)
Cite:Structure of a helicase-helicase loader complex reveals insights into the mechanism of bacterial primosome assembly.
Nat Commun, 4, 2013
1D89
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BU of 1d89 by Molmil
A DNA DODECAMER CONTAINING AN ADENINE TRACT CRYSTALLIZES IN A UNIQUE LATTICE AND EXHIBITS A NEW BEND
Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*AP*AP*AP*AP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*TP*TP*TP*TP*TP*CP*GP*CP*G)-3')
Authors:DiGabriele, A.D, Steitz, T.A.
Deposit date:1992-07-17
Release date:1993-07-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A DNA dodecamer containing an adenine tract crystallizes in a unique lattice and exhibits a new bend.
J.Mol.Biol., 231, 1993
1N8R
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BU of 1n8r by Molmil
Structure of large ribosomal subunit in complex with virginiamycin M
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10e, 50S ribosomal protein L13P, ...
Authors:Hansen, J.L, Moore, P.B, Steitz, T.A.
Deposit date:2002-11-21
Release date:2003-07-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit
J.Mol.Biol., 330, 2003
1NJI
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BU of 1nji by Molmil
Structure of chloramphenicol bound to the 50S ribosomal subunit
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10e, 50S ribosomal protein L13P, ...
Authors:Hansen, J.L, Moore, P.B, Steitz, T.A.
Deposit date:2002-12-31
Release date:2003-07-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit
J.Mol.Biol., 330, 2003
1G6N
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BU of 1g6n by Molmil
2.1 ANGSTROM STRUCTURE OF CAP-CAMP
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CATABOLITE GENE ACTIVATOR PROTEIN
Authors:Passner, J.M, Schultz, S.C, Steitz, T.A.
Deposit date:2000-11-07
Release date:2000-12-15
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Modeling the cAMP-induced allosteric transition using the crystal structure of CAP-cAMP at 2.1 A resolution.
J.Mol.Biol., 304, 2000
1QSL
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BU of 1qsl by Molmil
KLENOW FRAGMENT COMPLEXED WITH SINGLE-STRANDED SUBSTRATE AND EUROPIUM (III) ION
Descriptor: 5'-D(*GP*CP*TP*TP*AP*CP*GP*C)-3', DNA POLYMERASE I, EUROPIUM ION
Authors:Brautigam, C.A, Aschheim, K, Steitz, T.A.
Deposit date:1999-06-22
Release date:1999-06-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural elucidation of the binding and inhibitory properties of lanthanide (III) ions at the 3'-5' exonucleolytic active site of the Klenow fragment
Chem.Biol., 6, 1999
1GTS
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BU of 1gts by Molmil
STRUCTURAL BASIS FOR TRANSFER RNA AMINOACEYLATION BY ESCHERICHIA COLI GLUTAMINYL-TRNA SYNTHETASE
Descriptor: ADENOSINE MONOPHOSPHATE, PROTEIN (GLUTAMINYL-TRNA SYNTHETASE (E.C.6.1.1.18)), TRNAGLN
Authors:Perona, J.J, Steitz, T.A, Rould, M.A.
Deposit date:1993-09-15
Release date:1995-02-07
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for transfer RNA aminoacylation by Escherichia coli glutaminyl-tRNA synthetase.
Biochemistry, 32, 1993
2EX3
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BU of 2ex3 by Molmil
Bacteriophage phi29 DNA polymerase bound to terminal protein
Descriptor: DNA polymerase, DNA terminal protein, LEAD (II) ION
Authors:Kamtekar, S, Berman, A.J, Wang, J, de Vega, M, Blanco, L, Salas, M, Steitz, T.A.
Deposit date:2005-11-07
Release date:2006-03-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:The phi29 DNA polymerase:protein-primer structure suggests a model for the initiation to elongation transition
Embo J., 25, 2006
2FOT
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BU of 2fot by Molmil
Crystal structure of the complex between calmodulin and alphaII-spectrin
Descriptor: CALCIUM ION, Calmodulin, alpha-II spectrin Spectrin
Authors:Simonovic, M, Zhang, Z, Cianci, C.D, Steitz, T.A, Morrow, J.S.
Deposit date:2006-01-13
Release date:2006-09-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure of the calmodulin alphaII-spectrin complex provides insight into the regulation of cell plasticity.
J.Biol.Chem., 281, 2006
2GM4
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BU of 2gm4 by Molmil
An activated, tetrameric gamma-delta resolvase: Hin chimaera bound to cleaved DNA
Descriptor: 5'-D(*CP*AP*GP*TP*GP*TP*CP*CP*GP*AP*TP*AP*AP*TP*TP*TP*AP*TP*AP*AP*A)-3', 5'-D(*TP*TP*AP*TP*CP*GP*GP*AP*CP*AP*CP*TP*G)-3', Transposon gamma-delta resolvase
Authors:Kamtekar, S, Ho, R.S, Li, W, Steitz, T.A.
Deposit date:2006-04-05
Release date:2006-06-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Implications of structures of synaptic tetramers of gamma delta resolvase for the mechanism of recombination.
Proc.Natl.Acad.Sci.Usa, 103, 2006

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