4Z8C
Crystal structure of the Thermus thermophilus 70S ribosome bound to translation inhibitor oncocin
This is a non-PDB format compatible entry.
Summary for 4Z8C
Entry DOI | 10.2210/pdb4z8c/pdb |
Descriptor | 23S ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (59 entities in total) |
Functional Keywords | oncocin, antimicrobial peptide, antibiotic, 70s ribosome, inhibition of translation, peptidyl transferase inhibitors, 50s ribosomal subunit, peptide exit tunnel, ribosome-inhibitor complex, onc112, ribosome-antibiotic complex, ribosome/antibiotic |
Biological source | Escherichia coli More |
Total number of polymer chains | 110 |
Total formula weight | 4464601.48 |
Authors | Roy, R.N.,Lomakin, I.B.,Gagnon, M.G.,Steitz, T.A. (deposition date: 2015-04-08, release date: 2015-05-20, Last modification date: 2024-03-06) |
Primary citation | Roy, R.N.,Lomakin, I.B.,Gagnon, M.G.,Steitz, T.A. The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin. Nat.Struct.Mol.Biol., 22:466-469, 2015 Cited by PubMed: 25984972DOI: 10.1038/nsmb.3031 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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