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PDB: 135 件
5E6S
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BU of 5e6s by Molmil
Structures of leukocyte integrin aLB2: The aI domain, the headpiece, and the pocket for the internal ligand
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-L, ...
著者Springer, T.A, Sen, M.
登録日2015-10-10
公開日2016-03-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016
2VDP
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BU of 2vdp by Molmil
Integrin AlphaIIbBeta3 Headpiece Bound to Fibrinogen Gamma chain peptide,LGGAKQAGDV
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN, ...
著者Springer, T.A, Zhu, J, Xiao, T.
登録日2007-10-10
公開日2008-09-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
2VDO
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Integrin AlphaIIbBeta3 Headpiece Bound to Fibrinogen Gamma chain peptide, HHLGGAKQAGDV
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN, ...
著者Springer, T.A, Zhu, J, Xiao, T.
登録日2007-10-10
公開日2008-09-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
2VDK
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BU of 2vdk by Molmil
Re-refinement of Integrin AlphaIIbBeta3 Headpiece
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, CALCIUM ION, ...
著者Springer, T.A, Zhu, J, Xiao, T.
登録日2007-10-10
公開日2008-09-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
2VDN
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BU of 2vdn by Molmil
Re-refinement of Integrin AlphaIIbBeta3 Headpiece Bound to Antagonist Eptifibatide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, EPTIFIBATIDE, ...
著者Springer, T.A, Zhu, J, Xiao, T.
登録日2007-10-10
公開日2008-09-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
2VDL
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BU of 2vdl by Molmil
Re-refinement of Integrin AlphaIIbBeta3 Headpiece
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, CALCIUM ION, ...
著者Springer, T.A, Zhu, J, Xiao, T.
登録日2007-10-10
公開日2008-09-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
2VDM
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BU of 2vdm by Molmil
Re-refinement of Integrin AlphaIIbBeta3 Headpiece Bound to Antagonist Tirofiban
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
著者Springer, T.A, Zhu, J, Xiao, T.
登録日2007-10-10
公開日2008-09-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
5E6X
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BU of 5e6x by Molmil
Re-refinement of the Crystal Structure of the Plexin-Semaphorin-Integrin Domain/Hybrid Domain/I-EGF1 Segment from the Human Integrin b2 Subunit
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin beta-2
著者Springer, T.A, Sen, M.
登録日2015-10-10
公開日2016-03-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016
2VDR
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BU of 2vdr by Molmil
Integrin AlphaIIbBeta3 Headpiece Bound to a chimeric Fibrinogen Gamma chain peptide, LGGAKQRGDV
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN, ...
著者Springer, T.A, Zhu, J, Xiao, T.
登録日2007-10-10
公開日2008-09-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
2VC2
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BU of 2vc2 by Molmil
Re-refinement of Integrin AlphaIIbBeta3 Headpiece Bound to Antagonist L-739758
分子名称: 2-(S)-[N-(3-PYRIDYLSULFONYL)AMINO]-3-[[2-CARBONYL-5-[2-(PIPERIDIN-4-YL)ETHYL]-THIENO[2,3-B]THIOPHENEYL]AMINO]-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Springer, T.A, Zhu, J, Xiao, T.
登録日2007-09-18
公開日2008-09-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
2VDQ
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BU of 2vdq by Molmil
Integrin AlphaIIbBeta3 Headpiece Bound to a Chimeric Fibrinogen Gamma chain peptide, HHLGGAKQRGDV
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN, ...
著者Springer, T.A, Zhu, J, Xiao, T.
登録日2007-10-10
公開日2008-09-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182, 2008
5E6W
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BU of 5e6w by Molmil
Re-refinement of the Crystal Structure of the Plexin-Semaphorin-Integrin Domain/Hybrid Domain/I-EGF1 Segment from the Human Integrin b2 Subunit
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin beta-2
著者Springer, T.A, Sen, M.
登録日2015-10-10
公開日2016-03-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016
4G1M
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BU of 4g1m by Molmil
Re-refinement of alpha V beta 3 structure
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Springer, T.A, Mi, L, Zhu, J.
登録日2012-07-10
公開日2012-12-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Alpha V Beta 3 Integrin Crystal Structures and their Functional Implications
Biochemistry, 51, 2012
4HC1
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BU of 4hc1 by Molmil
Crystal structure of a loop deleted mutant of human MAdCAM-1 D1D2 complexed with Fab 10G3
分子名称: 10G3 heavy chain, 10G3 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Springer, T, Yu, Y, Zhu, J.
登録日2012-09-28
公開日2013-01-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.871 Å)
主引用文献A Different Fold with an Integrin-Binding Loop Specialized for Flexibility in Mucosal Addressin Cell Adhesion Molecule-1
TO BE PUBLISHED
4HCR
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BU of 4hcr by Molmil
Crystal structure of human MAdCAM-1 D1D2 complexed with Fab PF-547659
分子名称: Mucosal addressin cell adhesion molecule 1, PF-547659 heavy chain, PF-547659 light chain
著者Springer, T, Yu, Y, Zhu, J.
登録日2012-10-01
公開日2013-01-23
最終更新日2021-05-26
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A Different Fold with an Integrin-Binding Loop Specialized for Flexibility in Mucosal Addressin Cell Adhesion Molecule-1
TO BE PUBLISHED
4HD9
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BU of 4hd9 by Molmil
Crystal structure of native human MAdCAM-1 D1D2 domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Mucosal addressin cell adhesion molecule 1
著者Springer, T, Yu, Y, Zhu, J.
登録日2012-10-02
公開日2013-01-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A Different Fold with an Integrin-Binding Loop Specialized for Flexibility in Mucosal Addressin Cell Adhesion Molecule-1
TO BE PUBLISHED
4HBQ
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BU of 4hbq by Molmil
Crystal structure of a loop deleted mutant of Human MAdCAM-1 D1D2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Mucosal addressin cell adhesion molecule 1, ...
著者Springer, T, Yu, Y, Zhu, J.
登録日2012-09-28
公開日2013-01-23
最終更新日2021-05-26
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A Different Fold with an Integrin-Binding Loop Specialized for Flexibility in Mucosal Addressin Cell Adhesion Molecule-1
TO BE PUBLISHED
6OM2
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BU of 6om2 by Molmil
Crystal structure of atypical integrin alphaV beta8 with proTGF-beta1 ligand peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Wang, J.C, Springer, T.A.
登録日2019-04-17
公開日2019-12-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献General structural features that regulate integrin affinity revealed by atypical alpha V beta 8.
Nat Commun, 10, 2019
3K72
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BU of 3k72 by Molmil
Structure of integrin alphaX beta2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Xie, C, Zhu, J, Chen, X, Mi, L, Nishida, N, Springer, T.A.
登録日2009-10-11
公開日2010-01-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structure of an integrin with an alphaI domain, complement receptor type 4.
Embo J., 29, 2010
3K6S
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BU of 3k6s by Molmil
Structure of integrin alphaXbeta2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Xie, C, Zhu, J, Chen, X, Mi, L, Nishida, N, Springer, T.A.
登録日2009-10-09
公開日2010-01-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of an integrin with an alphaI domain, complement receptor type 4.
Embo J., 29, 2010
2OZ4
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BU of 2oz4 by Molmil
Structural Plasticity in IgSF Domain 4 of ICAM-1 Mediates Cell Surface Dimerization
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB FRAGMENT LIGHT CHAIN, ...
著者Chen, X, Kim, T.D, Carman, C.V, Mi, L, Song, G, Springer, T.A.
登録日2007-02-23
公開日2007-10-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural plasticity in Ig superfamily domain 4 of ICAM-1 mediates cell surface dimerization.
Proc.Natl.Acad.Sci.Usa, 104, 2007
8FXV
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BU of 8fxv by Molmil
Crystal structure of human proTGF-beta2 in complex with Nb18
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody clone 18, Transforming growth factor beta-2 proprotein
著者Le, V.Q, Springer, T.A.
登録日2023-01-25
公開日2023-06-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A specialized integrin-binding motif enables proTGF-beta 2 activation by integrin alpha V beta 6 but not alpha V beta 8.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FXS
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BU of 8fxs by Molmil
Crystal structure of human pro-TGF-beta2 in complex with Nb9
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody clone 9, Transforming growth factor beta-2 proprotein
著者Le, V.Q, Springer, T.A.
登録日2023-01-25
公開日2023-06-21
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献A specialized integrin-binding motif enables proTGF-beta 2 activation by integrin alpha V beta 6 but not alpha V beta 8.
Proc.Natl.Acad.Sci.USA, 120, 2023
8D3C
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BU of 8d3c by Molmil
VWF tubule derived from monomeric D1-A1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand factor
著者Anderson, J.R, Li, J, Springer, T.A, Brown, A.
登録日2022-06-01
公開日2022-07-06
最終更新日2022-10-05
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structures of VWF tubules before and after concatemerization reveal a mechanism of disulfide bond exchange.
Blood, 140, 2022
8D3D
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VWF tubule derived from dimeric D1-A1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand factor
著者Anderson, J.R, Li, J, Springer, T.A, Brown, A.
登録日2022-06-01
公開日2022-07-06
最終更新日2022-10-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structures of VWF tubules before and after concatemerization reveal a mechanism of disulfide bond exchange.
Blood, 140, 2022

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