2VDN

Re-refinement of Integrin AlphaIIbBeta3 Headpiece Bound to Antagonist Eptifibatide

Replaces:  1TY6

Summary for 2VDN

Related2VDK 2VDL 2VDM 2VDO 2VDP 2VDQ 2VDR
DescriptorINTEGRIN ALPHA-IIB, INTEGRIN BETA-3, EPTIFIBATIDE, ... (11 entities in total)
Functional Keywordscell adhesion-immune system complex, fibrinogen binding, platelet integrin alphaiibbeta3, glycoprotein, cell adhesion, membrane, integrin, receptor, antagonist, host-virus interaction, pyrrolidone carboxylic acid, transmembrane, phosphorylation, disease mutation, cleavage on pair of basic residues, cell adhesion/immune system
Biological sourceHOMO SAPIENS (HUMAN)
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Total number of polymer chains5
Total molecular weight151370.83
Authors
Springer, T.A.,Zhu, J.,Xiao, T. (deposition date: 2007-10-10, release date: 2008-09-02, Last modification date: 2019-02-06)
Primary citation
Springer, T.A.,Zhu, J.,Xiao, T.
Structural Basis for Distinctive Recognition of Fibrinogen Gammac Peptide by the Platelet Integrin Alphaiibbeta3.
J.Cell Biol., 182:791-, 2008
PubMed: 18710925 (PDB entries with the same primary citation)
DOI: 10.1083/JCB.200801146
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2163 0.3% 0.6% 3.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2vdn
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Molmil generated image of 2vdn
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Molmil generated image of 2vdn
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