6OM2

Crystal structure of atypical integrin alphaV beta8 with proTGF-beta1 ligand peptide

Summary for 6OM2

Entry DOI	10.2210/pdb6om2/pdb
Descriptor	Integrin alpha-V, CALCIUM ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (15 entities in total)
Functional Keywords	integrin, tgf-beta activation, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	238125.01
Authors	Wang, J.C.,Springer, T.A. (deposition date: 2019-04-17, release date: 2019-12-11, Last modification date: 2023-10-11)
Primary citation	Wang, J.,Su, Y.,Iacob, R.E.,Engen, J.R.,Springer, T.A. General structural features that regulate integrin affinity revealed by atypical alpha V beta 8. Nat Commun, 10:5481-5481, 2019 Cited by PubMed: 31792290 DOI: 10.1038/s41467-019-13248-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.77 Å)

Structure validation