6OM2

Crystal structure of atypical integrin alphaV beta8 with proTGF-beta1 ligand peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007155	biological_process	cell adhesion
A	0008305	cellular_component	integrin complex
C	0007155	biological_process	cell adhesion
C	0008305	cellular_component	integrin complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: in MIDAS binding site => ECO:0000269|PubMed:31792290, ECO:0007744|PDB:6OM1, ECO:0007744|PDB:6OM2

Chain	Residue	Details
B	ASP112
A	ASP292
A	ASP349
A	ASP351
A	ASP353
A	PHE355
A	ASP357
A	ASP414
A	ASP416
A	ASN418
A	TYR420
B	GLU212
A	ASP422
C	ASP230
C	ASN232
C	ASP234
C	ILE236
C	ASP238
C	ASP284
C	ASN286
C	ASP288
C	TYR290
D	ASP112
C	ASP292
C	ASP349
C	ASP351
C	ASP353
C	PHE355
C	ASP357
C	ASP414
C	ASP416
C	ASN418
C	TYR420
D	GLU212
C	ASP422
A	ASP238
A	ASP284
A	ASN286
A	ASP288
A	TYR290

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: in MIDAS binding site => ECO:0000269|PubMed:31792290, ECO:0007744|PDB:6OM2

Chain	Residue	Details
B	SER114
D	SER114

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site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: in LIMBS binding site => ECO:0000269|PubMed:31792290, ECO:0007744|PDB:6OM1, ECO:0007744|PDB:6OM2

Chain	Residue	Details
B	ASP151
B	ASN207
B	ASP209
B	PRO211
D	ASP151
D	ASN207
D	ASP209
D	PRO211

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site_id	SWS_FT_FI4
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
B	ASN191
B	ASN414
D	ASN191
D	ASN414

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site_id	SWS_FT_FI5
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:31792290, ECO:0007744|PDB:6OM1

Chain	Residue	Details
B	ASN360
B	ASN379
D	ASN360
D	ASN379

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site_id	SWS_FT_FI6
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:31792290, ECO:0007744|PDB:6OM1, ECO:0007744|PDB:6OM2

Chain	Residue	Details
B	ASN389
D	ASN389

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